Research Use Only. Retatrutide is sold as a chemical reagent for in-vitro laboratory research. It is not a drug, supplement, or compounded preparation, and it is not for human or veterinary use. Wholesale Peptide Supply is not a pharmacy or compounding facility under 503A or 503B.
Wholesale Retatrutide — Bulk Research Supply
Buy Retatrutide wholesale and in bulk from a US-based research peptide supplier. Every lot is sourced in the USA and third-party third-party tested via HPLC/MS. Bulk Retatrutide is quoted by dose and volume across 100–1,000 vials, mix-and-match across the catalog.
Retatrutide is a synthetic investigational peptide developed as a multi-pathway agonist, representing the next generation of metabolic research compounds. It activates multiple target receptor subtypes for broad systemic effects studied in preclinical models.
Wholesale Catalog
Available Doses
Published per-vial wholesale pricing for Retatrutide. Sold in boxes of 10 vials with a 100-vial order minimum you can mix and match across compounds; volume pricing applies at 1,000+ vials. Contact us for larger or custom-volume quotes — typically answered within 10 minutes during business hours.
Retatrutide 10mg
CAS 2381089-83-2 · GLP-1 & Metabolic
$23/vial · under 1,000 vials · $15/vial · 1,000+
Sold in boxes of 10 vials · 100-vial order minimum (mix & match) · 1,000+ unlocks the lower price
Retatrutide 30mg
CAS 2381089-83-2 · GLP-1 & Metabolic
$40/vial · under 1,000 vials · $28/vial · 1,000+
Sold in boxes of 10 vials · 100-vial order minimum (mix & match) · 1,000+ unlocks the lower price
Retatrutide 60mg
CAS 2381089-83-2 · GLP-1 & Metabolic
$65/vial · under 1,000 vials · $51/vial · 1,000+
Sold in boxes of 10 vials · 100-vial order minimum (mix & match) · 1,000+ unlocks the lower price
Overview
Retatrutide is a synthetic investigational peptide developed as a multi-pathway agonist, representing the next generation of metabolic research compounds. It activates multiple target receptor subtypes for broad systemic effects studied in preclinical models.
History
Builds on decades of single- and dual-agonist research; uniquely integrates three pathway targets.
Structure and mechanism
Retatrutide is a synthetic peptide engineered as a triple agonist — active at three distinct receptor targets simultaneously — representing the current frontier of multi-pathway metabolic research compounds. It extends the design logic of single-pathway (semaglutide) and dual-pathway (tirzepatide) agonists by integrating a third pathway, glucagon-receptor activity, alongside the two.
In preclinical laboratory models the compound is studied for the broad, multi-system signaling that arises from co-activating three pathways, and it is frequently used as the reference point in triple- vs. dual-agonist comparative work. Its molecular weight (4,845.44 g/mol) and formula (C₂₂₁H₃₄₂N₄₆O₆₈) sit close to tirzepatide's, but its receptor-engagement profile is distinct.
Reconstitution and handling (research use)
Wholesale retatrutide ships as a lyophilized powder. For in-vitro laboratory use it is reconstituted with bacteriostatic or sterile water, with diluent volume chosen to reach the assay's target concentration. Lyophilized material is generally stored at -20°C and protected from light; reconstituted solution is refrigerated at 2–8°C and used within the working window the study defines.
These notes cover general laboratory handling of a chemical reagent only — not human or veterinary use.
Wholesale sourcing notes
Retatrutide is among the fastest-growing compounds in wholesale research demand, stocked in 10 mg and higher presentations. Every lot is US-sourced and independently verified by a third-party lab via HPLC/MS for identity, purity, and quantitation, with a per-lot COA available as an add-on.
Pricing is quoted by volume across 100, 250, 500, and 1,000-vial bands under a 100-vial mix-and-match minimum, with a lower price band unlocking at 1,000 vials across the whole order.
Key Areas of Research
- Receptor binding and cascades
- Pathway subtypes and modulation
- Vascular lipid pathways
- Multi-system signaling
- Triple- vs. dual-agonist comparative studies
References
- Jastreboff A.M. et al. (2023). Triple-hormone-receptor agonist retatrutide for obesity. NEJM 389:514–526.
- Coskun T. et al. (2022). LY3437943 triple agonist. Mol Metabol 69:101470.
- Rosenstock J. et al. (2023). Retatrutide, a GIP/GLP-1/glucagon receptor agonist. Lancet, 402(10401):529–544.
Retatrutide — Frequently Asked Questions
- What is Retatrutide?
- Retatrutide is a synthetic investigational peptide developed as a multi-pathway agonist, representing the next generation of metabolic research compounds. It activates multiple target receptor subtypes for broad systemic effects studied in preclinical models.
- What is the CAS number for Retatrutide?
- The CAS number for Retatrutide is 2381089-83-2. Its molecular formula is C₂₂₁H₃₄₂N₄₆O₆₈ (MW 4,845.44 g/mol).
- What doses of Retatrutide are available wholesale?
- Wholesale Peptide Supply stocks Retatrutide in 10mg, 30mg, 60mg. Wholesale pricing is provided by quote based on order volume across 100–1,000 vials.
- Is Retatrutide third-party tested?
- Yes. Every lot of Retatrutide is tested by an independent third-party laboratory using HPLC/MS, and a per-lot Certificate of Analysis documenting identity and purity is available as a paid add-on.
- Is Retatrutide for human use?
- No. Retatrutide is sold strictly as a chemical reagent for in-vitro laboratory research and is not for human or veterinary use. Wholesale Peptide Supply is not a pharmacy or compounding facility.
- How do I get wholesale pricing for Retatrutide?
- Request a quote through our contact form or open a wholesale account. An account manager replies with volume pricing and lead times, typically within 10 minutes during business hours.
- Can I order Retatrutide in bulk?
- Yes. Retatrutide is available for bulk and wholesale orders, quoted by dose and volume across 100, 250, 500, and 1,000-vial bands. Submit the doses and quantities you need for a bulk quote; all material is sourced in the USA and third-party HPLC/MS tested.
- How does retatrutide compare to tirzepatide and semaglutide?
- Retatrutide is a triple-pathway agonist (three receptor targets), tirzepatide is dual-pathway, and semaglutide is single-pathway. All three are distinct research compounds and are not interchangeable in laboratory models; retatrutide is the newest and is commonly used as the reference in triple-agonist comparative studies.
- Is wholesale retatrutide third-party tested?
- Yes. Every lot of retatrutide is US-sourced and independently tested by a third-party lab via HPLC/MS, confirming identity, purity, and quantitation. A per-lot Certificate of Analysis is available as a paid add-on with your order.
Research Use Only
All products are intended solely for laboratory research purposes and are not for human or animal consumption. Must be handled by qualified professionals.
Related Compounds
GLP-1 & Metabolic
Semaglutide
Semaglutide is a synthetic peptide analog that functions as a long-acting pathway agonist, structurally modified for extended half-life and improved target binding affinity. It is studied in preclinical and laboratory models for its ability to activate target pathways and modulate downstream molecular signaling associated with endocrine regulation.
View details →GLP-1 & Metabolic
Tirzepatide
Tirzepatide is a synthetic peptide that functions as a dual pathway agonist, designed as a once-weekly investigational compound studied in preclinical laboratory models for receptor-mediated signaling and modulation of downstream cascades.
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Cagrilintide
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TB-500
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GHK-Cu
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