Research Use Only. Semaglutide is sold as a chemical reagent for in-vitro laboratory research, not for human or veterinary use. It is not a drug, supplement, or compounded preparation. It must be handled by qualified professionals. Wholesale Peptide Supply is not a pharmacy or compounding facility under 503A or 503B.
Wholesale Semaglutide — Bulk Research Supply
Available sizes
In-stock orders ship same day when paid by 1 pm PT, Mon–Fri. Overnight available.
Buy Semaglutide wholesale and in bulk from a US-based research peptide supplier. Every lot is sourced in the USA and third-party tested, with the lab and method on each lot's certificate. Bulk Semaglutide is sold at published per-vial prices from a 3-kit (30-vial) order minimum, mix and match across doses and compounds; lower prices are earned at 10 kits and again at 100 kits in the order, mix and match.
Semaglutide is a synthetic peptide analog that functions as a long-acting pathway agonist, structurally modified for extended half-life and improved target binding affinity. It is studied in preclinical and laboratory models for its ability to activate target pathways and modulate downstream molecular signaling associated with endocrine regulation.
Wholesale Catalog
Available Doses
Published per-vial wholesale pricing for Semaglutide. Sold in kits of 10 vials with a 3-kit (30-vial) order minimum, mix and match across doses and compounds; lower prices apply once your order reaches 10 kits and again at 100 kits (1,000 vials). Contact us for larger or custom-volume quotes — answered the same day. Urgent? Text or call (714) 625-9215 — you’ll reach a real person in the United States, not a chatbot or an overseas call center.
Semaglutide 5mg
WPSS5 · CAS 910463-68-2 · GLP-1 & Metabolic
Discontinued
This product is no longer stocked and is not being restocked.
Semaglutide 10mg
WPSS10 · CAS 910463-68-2 · GLP-1 & Metabolic
- 1–9 kits
- $19.41/vial$17.47 paying by card
- 10–99 kits
- $15.53/vial$13.97 paying by card
- 100+ kits
- $12.42/vial$11.18 paying by card
10% off with card Every product, every volume band — taken off at checkout when you choose card.
Sold in kits of 10 vials · 3-kit order minimum, mix and match · price set by the total kits in your order (BAC water not counted)
Semaglutide 20mg
WPSS20 · CAS 910463-68-2 · GLP-1 & Metabolic
Discontinued
This product is no longer stocked and is not being restocked.
Semaglutide 30mg
WPSS30 · CAS 910463-68-2 · GLP-1 & Metabolic
- 1–9 kits
- $35.94/vial$32.34 paying by card
- 10–99 kits
- $28.75/vial$25.88 paying by card
- 100+ kits
- $23/vial$20.70 paying by card
10% off with card Every product, every volume band — taken off at checkout when you choose card.
Sold in kits of 10 vials · 3-kit order minimum, mix and match · price set by the total kits in your order (BAC water not counted)
Questions? Text a rep or call (714) 625-9215 — a real person in the US answers.
Overview
Semaglutide is a synthetic peptide analog that functions as a long-acting pathway agonist, structurally modified for extended half-life and improved target binding affinity. It is studied in preclinical and laboratory models for its ability to activate target pathways and modulate downstream molecular signaling associated with endocrine regulation.
History
Research into endocrine peptide biology began in the 1980s with the identification of key peptide roles in signaling pathways. Semaglutide was developed with structural modifications — a C18 fatty diacid chain attached via a linker to lysine at position 26 and substitutions at positions 8 and 34 — to improve albumin binding and extend duration of action.
Structure and mechanism
Semaglutide is a 31-amino-acid peptide analog derived from the native GLP-1 backbone. Two substitutions — Aib at position 8 (which resists enzymatic cleavage) and Arg at position 34 — are paired with a C18 fatty diacid chain attached through a γGlu-2xOEG linker to lysine at position 26. That acylation drives reversible albumin binding, which is the structural basis for the compound's extended half-life relative to native GLP-1.
In laboratory models, semaglutide is studied as a long-acting, single-pathway receptor agonist. Research interest centers on receptor binding kinetics, downstream cAMP/PKA signaling, and the comparative behavior of single-pathway agonists against the dual- and triple-pathway compounds (tirzepatide, retatrutide) increasingly used as reference points.
Reconstitution and handling (research use)
Wholesale semaglutide ships as a lyophilized powder. For in-vitro laboratory work it is typically reconstituted with bacteriostatic or sterile water, with the diluent volume chosen to hit the concentration a given assay calls for. Lyophilized material is generally stored at -20°C and protected from light; reconstituted solution is kept refrigerated at 2–8°C and used within the working window appropriate to the study.
These notes describe general laboratory handling of a chemical reagent only. They are not directions for human or veterinary use.
Wholesale sourcing notes
Semaglutide is the highest-demand compound in the current wholesale market, stocked here in 10 mg and 30 mg presentations (the 5 mg and 20 mg vials are discontinued). Every lot moves through a controlled US-based supply chain and is verified by an independent third-party lab for identity, purity, and quantitation, with a per-lot Certificate of Analysis included free with every order.
Wholesale pricing is published in three bands set by the order's total kits — 1–9 kits, 10–99 kits and 100+ kits (1,000 vials) — from a 3-kit (30-vial) order minimum, mix and match across doses and compounds.
Buying Semaglutide in Bulk
Semaglutide is sold here to qualified wholesale buyers as a lyophilized research peptide in 10mg and 30mg vials, packed ten to a kit. Wholesale pricing for both doses is published below, a per-lot certificate of analysis is included free with every order, and in-stock orders ship from the US the same business day when paid before the daily cutoff.
| Dose | 1–9 kits | 10–99 kits | Per mg at 10+ | 100+ kits in order |
|---|---|---|---|---|
| Semaglutide 10mg | $194.06/kit ($19.41/vial) | $155.25/kit ($15.53/vial) | $1.55 | $124.20/kit ($12.42/vial) |
| Semaglutide 30mg | $359.38/kit ($35.94/vial) | $287.50/kit ($28.75/vial) | $0.96 | $230.00/kit ($23.00/vial) |
Wholesale semaglutide by dose: 10mg and 30mg
Both doses are sold in kits of 10 vials. The table above shows the price of each kit, what it works out to per vial and per milligram, and the lower price at volume, so the two can be compared side by side before you order. The 5mg and 20mg vials are discontinued.
The minimum is 3 kits per order, mix and match, so a first order can be 3 kits of a single dose, or semaglutide doses combined with tirzepatide and other compounds from the catalog.
How to order semaglutide wholesale
Bulk semaglutide is ordered online, right on this page. Choose the doses and number of kits you need and add them to your order. At checkout you enter your business details and shipping address and choose how to pay: wire, ACH, Zelle or card.
An account manager confirms availability, and the order ships once payment clears. For quantities or configurations outside the catalog, request a custom quote and we will price it for you.
Semaglutide minimum order and volume pricing
The minimum is 3 kits (30 vials) per order, mix and match across doses and compounds. Pricing is set by the order's total kits: an order of 1–9 kits pays the first rate in the table, 10 kits or more the lower rate, and 100 kits (1,000 vials) or more the volume rate. Kits of other compounds in the same order count toward the band; BAC water is priced on its own.
Where semaglutide fits in a GLP-1 research line
Semaglutide is the single-pathway reference compound of the GLP-1 category: it acts at the GLP-1 receptor alone, where tirzepatide is a dual agonist and retatrutide a triple agonist. That is why it is commonly stocked as the baseline against which the multi-pathway compounds are compared.
The catalog also carries a cagrilintide / semaglutide blend, which pairs semaglutide with a long-acting amylin analog in one vial, for work on the two pathways together.
Lyophilized semaglutide with a certificate for every lot
Semaglutide ships as a lyophilized powder in sealed vials. Each lot is tested by an independent third-party laboratory, and the certificate for your lot is included free with every order, issued in the name of Wholesale Peptide Supply. The certificates on file are listed on this page with the lab, lot, test date and method for each.
Semaglutide is sold as a research chemical for in-vitro laboratory use only. It is not for human or veterinary use, and Wholesale Peptide Supply is not a pharmacy or compounding facility. We sell for resale, so every account needs a valid resale certificate on file.
Also in this research area
If you stock Semaglutide, see also Cagrilintide / Semaglutide Blend. Each page lists its sizes and per-vial pricing.
Certificates of Analysis
3 certificates are on file for Semaglutide — open any one to read the full report.
| Lot / Lab | Dose | Tested | Purity | Certificate |
|---|---|---|---|---|
| 100089-0949Optiq Health LabsRP-HPLC / LC-MS | 10mg | 2026-08-20 | — | |
| 100032-0319Optiq Health LabsRP-HPLC / LC-MS | 20mg | 2026-07-29 | — | |
| 100032-0329Optiq Health LabsRP-HPLC / LC-MS | 30mg | 2026-07-29 | — |
Key Areas of Research
- Signaling: pathway dynamics, downstream cascades
- Endocrine: target pathway modulation
- Systemic: lipid pathways, signaling markers
- Receptor binding: albumin-mediated half-life extension
- Comparative studies: single- vs. dual-pathway agonists
References
- Marso S.P. et al. (2016). Semaglutide and cardiovascular outcomes in patients with type 2 diabetes. NEJM, 375:1834–1844.
- Knudsen L.B. et al. (2000). Glucagon-like peptide receptor agonists. Diabetes, 49(12):1978–1984.
- Lau J. et al. (2015). Discovery of the once-weekly GLP-1 analog semaglutide. J Med Chem, 58(18):7370–7380.
- Nauck M.A. & Meier J.J. (2018). Incretin hormones: their role in health and disease. Diabetes Obes Metab, 20(Suppl 1):5–21.
Semaglutide — Frequently Asked Questions
- What is Semaglutide?
- Semaglutide is a synthetic peptide analog that functions as a long-acting pathway agonist, structurally modified for extended half-life and improved target binding affinity. It is studied in preclinical and laboratory models for its ability to activate target pathways and modulate downstream molecular signaling associated with endocrine regulation.
- What is the CAS number for Semaglutide?
- The CAS number for Semaglutide is 910463-68-2. Its molecular formula is C₁₈₇H₂₉₁N₄₅O₅₉ (MW 4,113.6 g/mol).
- What doses of Semaglutide are available wholesale?
- Wholesale Peptide Supply stocks Semaglutide in 10mg, 30mg. The per-vial wholesale price of every dose is published on this page, and the minimum is 3 kits (30 vials) per order, mix and match across doses and compounds.
- Is Semaglutide third-party tested?
- Yes. Every lot of Semaglutide is tested by an independent third-party laboratory, and a per-lot Certificate of Analysis is included with every order at no charge, issued in the name of Wholesale Peptide Supply. The most recent published lot, 100089-0949 (10mg), was tested by Optiq Health Labs on 20 August 2026 by RP-HPLC / LC-MS. Every lot on file is listed with its certificate on this page.
- Is Semaglutide for human use?
- No. Semaglutide is sold strictly as a chemical reagent for in-vitro laboratory research and is not for human or veterinary use. Wholesale Peptide Supply is not a pharmacy or compounding facility.
- How do I get wholesale pricing for Semaglutide?
- It is published on this page, with no quote or account needed: a per-vial price for each dose from 1 kit (3 kits per order, mix and match), a lower price once the order reaches 10 kits in total (mix and match), and a lower one again at 100 kits (1,000 vials) or more. Add the doses you need to an order request and an account manager confirms availability and sends the invoice the same day. For anything urgent, text or call (714) 625-9215 to reach a real person in the US.
- Can I order Semaglutide in bulk?
- Yes. Semaglutide is available for bulk and wholesale orders at the per-vial prices published on this page, from a 3-kit (30-vial) order minimum, mix and match across doses and compounds, with lower prices at 10 kits and at 100 kits (1,000 vials) in the order, mix and match. For quantities or configurations outside the catalog, request a custom quote.
- How is wholesale semaglutide reconstituted for research?
- Semaglutide ships as a lyophilized powder and is reconstituted with bacteriostatic or sterile water for in-vitro laboratory use, with diluent volume selected for the target assay concentration. Lyophilized material is typically stored at -20°C; reconstituted solution is kept at 2–8°C. This describes reagent handling only, not human or veterinary use.
- What is the difference between semaglutide and tirzepatide?
- Semaglutide is a single-pathway GLP-1 receptor agonist; tirzepatide is a dual-pathway agonist active at two receptor targets. They are not interchangeable in research models. See the wholesale tirzepatide page or the tirzepatide-vs-semaglutide guide for a full comparison.
- What should a semaglutide COA show?
- A complete semaglutide Certificate of Analysis confirms identity by HPLC retention time and mass spec, reports a quantitative purity percentage, verifies per-vial dose, and ties to a lot number traceable to the production run — issued by the independent testing lab, not a first-party summary.
- How much does bulk semaglutide cost?
- At published wholesale pricing, on an order of 10 to 99 kits (mix and match), Semaglutide 10mg is $155.25 per 10-vial kit ($15.53 per vial) and 30mg is $287.50 per 10-vial kit ($28.75 per vial). Orders of 1 to 9 kits in total pay $194.06 for 10mg and $359.38 for 30mg per kit. An order of 100 or more kits lowers the kit price to $124.20 for 10mg and $230.00 for 30mg. Flat-rate shipping is added once per order, and a per-lot certificate of analysis is included.
Related Compounds
GLP-1 & Metabolic
Tirzepatide
Tirzepatide is a synthetic peptide that functions as a dual pathway agonist, designed as a once-weekly investigational compound studied in preclinical laboratory models for receptor-mediated signaling and modulation of downstream cascades.
View details →GLP-1 & Metabolic
Retatrutide
Retatrutide is a synthetic investigational peptide developed as a multi-pathway agonist, representing the next generation of metabolic research compounds. It activates multiple target receptor subtypes for broad systemic effects studied in preclinical models.
View details →GLP-1 & Metabolic
Cagrilintide
Cagrilintide is a synthetic, long-acting analog of amylin, studied for activation of target receptor pathways and characterization of endocrine and neuroendocrine signaling.
View details →GLP-1 & Metabolic
AOD-9604
AOD-9604 is a synthetic peptide fragment derived from the C-terminus of the somatotropin sequence, studied for its effects on lipolytic and anti-lipogenic pathways and β3-adrenergic signaling.
View details →GLP-1 & Metabolic
HGH Fragment 176-191
HGH Fragment 176-191 is the C-terminal 16-residue fragment of human growth hormone, carrying an intramolecular disulfide bridge. It is studied in laboratory models of lipolytic signaling separated from the growth-promoting activity of the full hormone.
View details →GLP-1 & Metabolic
Triple Antagonist Liquid Spray
A combined metabolic research solution supplied as an atomized solution in a metered spray bottle. Composition is stated on the certificate of analysis for each lot.
View details →Secretagogue Peptides
Ipamorelin
Ipamorelin is a synthetic pentapeptide and selective secretagogue-type agonist with minimal off-target pathway interference, used to study endocrine signaling and somatotroph axis modulation.
View details →Recovery & Structural
BPC-157
BPC-157 is a synthetic pentadecapeptide composed of 15 amino acids, originally derived from a naturally occurring protein fragment in gastric tissue. It has been studied extensively for its potential influence on molecular signaling, structural remodeling, and angiogenic processes.
View details →