Research Use Only. TB-500 is sold as a chemical reagent for in-vitro laboratory research, not for human or veterinary use. It is not a drug, supplement, or compounded preparation. It must be handled by qualified professionals. Wholesale Peptide Supply is not a pharmacy or compounding facility under 503A or 503B.
Wholesale TB-500 — Bulk Research Supply
Available sizes
In-stock orders ship same day when paid by 1 pm PT, Mon–Fri. Overnight available.
Buy TB-500 wholesale and in bulk from a US-based research peptide supplier. Every lot is sourced in the USA and third-party tested, with the lab and method on each lot's certificate. Bulk TB-500 is quoted by dose and volume from a 3-kit (30-vial) order minimum, mix and match across doses and compounds; lower prices are earned at 10 kits and again at 100 kits in the order, mix and match.
TB-500 is a synthetic peptide fragment derived from thymosin beta-4, studied for its influence on matrix remodeling, angiogenesis, and molecular migration.
Wholesale Catalog
Available Doses
Published per-vial wholesale pricing for TB-500. Sold in kits of 10 vials with a 3-kit (30-vial) order minimum, mix and match across doses and compounds; lower prices apply at 10 kits and at 1,000+ vials in the order. Contact us for larger or custom-volume quotes — answered the same day. Urgent? Text or call (714) 625-9215 — you’ll reach a real person in the United States, not a chatbot or an overseas call center.
TB-500 10mg
WPSTB10 · CAS 77591-33-4 · Recovery & Structural
- 1–9 kits
- $39.53/vial$35.58 paying by card
- 10–99 kits
- $31.63/vial$28.46 paying by card
- 100+ kits
- $25.30/vial$22.77 paying by card
10% off with card Every product, every volume band — taken off at checkout when you choose card.
Sold in kits of 10 vials · 3-kit order minimum, mix and match · price set by the total kits in your order (BAC water not counted)
Questions? Text a rep or call (714) 625-9215 — a real person in the US answers.
Overview
TB-500 is a synthetic peptide fragment derived from thymosin beta-4, studied for its influence on matrix remodeling, angiogenesis, and molecular migration.
History
Thymosin Beta-4 was first isolated in the 1960s by Allan L. Goldstein. TB-500 was synthesized as a research fragment to study Tβ4's signaling functions.
Structure and mechanism
TB-500 is a synthetic fragment corresponding to the active region of thymosin beta-4, the actin-sequestering protein first isolated by Allan Goldstein's group in the 1960s. Rather than reproducing the full Tβ4 protein, the fragment isolates the sequence associated with actin binding, which is what makes it useful as a research reagent: it lets the actin-related signaling be studied without the rest of the parent molecule.
In laboratory models the research areas follow the parent protein's known biology — extracellular matrix and collagen remodeling, angiogenesis and vascular endpoints, and cell migration in epithelial systems. Smart and colleagues' 2007 work on progenitor mobilization remains a common reference point. At 4,963.5 g/mol (C₂₁₂H₃₅₀N₅₆O₇₈S) it is a mid-size peptide and is frequently studied alongside BPC-157 in comparative structural-recovery work.
Reconstitution and handling (research use)
Wholesale TB-500 ships lyophilized. For in-vitro use it is reconstituted with bacteriostatic or sterile water introduced slowly down the vial wall; at roughly 5 kDa it is large enough that vigorous agitation risks shear and foaming, so gentle swirling until the cake clears is the standard approach.
Lyophilized material is generally stored at -20°C protected from light, and reconstituted solution refrigerated at 2–8°C and used within the working window the study defines. Aliquoting before freezing avoids repeated freeze-thaw cycles. These notes cover general laboratory handling of a chemical reagent only — not human or veterinary use.
Wholesale sourcing notes
TB-500 is stocked wholesale in a 10 mg presentation. Every lot is US-sourced and independently verified by a third-party lab for identity, purity, and quantitation, with a per-lot COA included in every order.
It is one of the more frequently ordered compounds in the recovery and structural category, and is commonly paired with BPC-157 — a BPC/TB-500 blend is stocked as a separate line for labs wanting both in a single vial. Pricing is in three bands set by the order's total kits — 1–9 kits, 10–99 kits and 100+ kits (1,000 vials), mix and match — from a 3-kit (30-vial) order minimum, mix and match across doses and compounds.
Key Areas of Research
- Structural: collagen, matrix, tendon/ligament
- Vascular: angiogenesis, nitric oxide, remodeling
- Epithelial: migration, signaling, matrix
References
- Goldstein A.L. et al. (2005). Discovery of thymosins. Ann N Y Acad Sci 1042:1–8.
- Smart N. et al. (2007). Thymosin beta-4 progenitor mobilization. Nature 445:177–182.
TB-500 — Frequently Asked Questions
- What is TB-500?
- TB-500 is a synthetic peptide fragment derived from thymosin beta-4, studied for its influence on matrix remodeling, angiogenesis, and molecular migration.
- What is the CAS number for TB-500?
- The CAS number for TB-500 is 77591-33-4. Its molecular formula is C₂₁₂H₃₅₀N₅₆O₇₈S (MW 4,963.5 g/mol).
- What doses of TB-500 are available wholesale?
- Wholesale Peptide Supply stocks TB-500 in 10mg. Wholesale pricing is provided by quote based on order volume, from a 3-kit (30-vial) order minimum, mix and match across doses and compounds.
- Is TB-500 third-party tested?
- Yes. Every lot of TB-500 is tested by an independent third-party laboratory, and a per-lot Certificate of Analysis documenting identity and purity is included with every order at no charge, issued in the name of Wholesale Peptide Supply.
- Is TB-500 for human use?
- No. TB-500 is sold strictly as a chemical reagent for in-vitro laboratory research and is not for human or veterinary use. Wholesale Peptide Supply is not a pharmacy or compounding facility.
- How do I get wholesale pricing for TB-500?
- Request a quote through our contact form or open a wholesale account. An account manager replies with volume pricing and lead times the same day. For anything urgent, text or call (714) 625-9215 to reach a real person in the US.
- Can I order TB-500 in bulk?
- Yes. TB-500 is available for bulk and wholesale orders, quoted by dose and volume, from a 3-kit (30-vial) order minimum, mix and match across doses and compounds, with lower prices at 10 kits and at 100 kits (1,000 vials) in the order. Submit the doses and quantities you need for a bulk quote.
- Is TB-500 the same as thymosin beta-4?
- No. Thymosin beta-4 (Tβ4) is the full parent protein, first isolated in the 1960s. TB-500 is a shorter synthetic fragment corresponding to its active actin-binding region, synthesized so that region can be studied on its own. They are distinct materials and are not interchangeable in laboratory models.
- What doses of TB-500 are available wholesale?
- TB-500 is stocked in 10 mg vials under CAS 77591-33-4, with per-lot third-party verification. A BPC/TB-500 blend is also stocked as a separate catalog line for combined structural research.
Related Compounds
Recovery & Structural
BPC-157
BPC-157 is a synthetic pentadecapeptide composed of 15 amino acids, originally derived from a naturally occurring protein fragment in gastric tissue. It has been studied extensively for its potential influence on molecular signaling, structural remodeling, and angiogenic processes.
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BPC/TB5 Blend
The BPC-157 + TB-500 blend combines two of the most researched structural and recovery peptides into a single research formulation, studied across structural, vascular, and epithelial models.
View details →Recovery & Structural
BPC-157 Liquid Spray
BPC-157 supplied as an atomized solution in a metered spray bottle. A pentadecapeptide fragment of body-protection compound, supplied in solution rather than as a lyophilised solid.
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Wolverine Blend Liquid Spray (BPC-157 / TB-500)
A combined atomized solution of BPC-157 and TB-500, supplied together in one metered spray bottle.
View details →GLP-1 & Metabolic
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