What is the CAS number for TB-500?

The CAS number for TB-500 is 77591-33-4. Its molecular formula is C₂₁₂H₃₅₀N₅₆O₇₈S (MW 4,963.5 g/mol).

What doses of TB-500 are available wholesale?

Wholesale Peptide Supply stocks TB-500 in 5mg, 10mg. Wholesale pricing is provided by quote based on order volume across 100–1,000 vials.

Is TB-500 third-party tested?

Yes. Every lot of TB-500 is tested by an independent third-party laboratory using HPLC/MS, and a per-lot Certificate of Analysis documenting identity and purity is available as a paid add-on.

Is TB-500 for human use?

No. TB-500 is sold strictly as a chemical reagent for in-vitro laboratory research and is not for human or veterinary use. Wholesale Peptide Supply is not a pharmacy or compounding facility.

How do I get wholesale pricing for TB-500?

Request a quote through our contact form or open a wholesale account. An account manager replies with volume pricing and lead times, typically within 10 minutes during business hours.

Can I order TB-500 in bulk?

Yes. TB-500 is available for bulk and wholesale orders, quoted by dose and volume, with the lower price earned per compound at 100 kits (1,000 vials). Submit the doses and quantities you need for a bulk quote; all material is sourced in the USA and third-party HPLC/MS tested.

Is TB-500 the same as thymosin beta-4?

No. Thymosin beta-4 (Tβ4) is the full parent protein, first isolated in the 1960s. TB-500 is a shorter synthetic fragment corresponding to its active actin-binding region, synthesized so that region can be studied on its own. They are distinct materials and are not interchangeable in laboratory models.

What doses of TB-500 are available wholesale?

TB-500 is stocked in 5 mg and 10 mg vials under CAS 77591-33-4, each with per-lot HPLC/MS verification. A BPC/TB-500 blend is also stocked as a separate catalog line for combined structural research.

Research Use Only. TB-500 is sold as a chemical reagent for in-vitro laboratory research. It is not a drug, supplement, or compounded preparation, and it is not for human or veterinary use. Wholesale Peptide Supply is not a pharmacy or compounding facility under 503A or 503B.

Recovery & StructuralCAS 77591-33-4

Wholesale TB-500 — Bulk Research Supply

Buy TB-500 wholesale and in bulk from a US-based research peptide supplier. Every lot is sourced in the USA and third-party third-party tested via HPLC/MS. Bulk TB-500 is quoted by dose and volume from a 100-vial mix-and-match minimum; volume pricing is earned per compound at 100 kits.

TB-500 is a synthetic peptide fragment derived from thymosin beta-4, studied for its influence on matrix remodeling, angiogenesis, and molecular migration.

Wholesale Catalog

Available Doses

Published per-vial wholesale pricing for TB-500. Sold in kits of 10 vials with a 100-vial order minimum you can mix and match across compounds; volume pricing applies at 1,000+ vials. Contact us for larger or custom-volume quotes — typically answered within 10 minutes during business hours.

TB-500 5mg

WPSTB5 · CAS 77591-33-4 · Recovery & Structural

$18.69/vial · under 100 kits · $14.95/vial · 100+ kits of this item

Sold in kits of 10 vials · 100-vial order minimum (mix & match across compounds) · 100+ kits of this item unlocks the lower price

Quantity

10 vials

1 kit

Request a custom quote

TB-500 10mg

WPSTB10 · CAS 77591-33-4 · Recovery & Structural

$31.63/vial · under 100 kits · $25.30/vial · 100+ kits of this item

Sold in kits of 10 vials · 100-vial order minimum (mix & match across compounds) · 100+ kits of this item unlocks the lower price

Quantity

10 vials

1 kit

Request a custom quote

Overview

TB-500 is a synthetic peptide fragment derived from thymosin beta-4, studied for its influence on matrix remodeling, angiogenesis, and molecular migration.

History

Thymosin Beta-4 was first isolated in the 1960s by Allan L. Goldstein. TB-500 was synthesized as a research fragment to study Tβ4's signaling functions.

Structure and mechanism

TB-500 is a synthetic fragment corresponding to the active region of thymosin beta-4, the actin-sequestering protein first isolated by Allan Goldstein's group in the 1960s. Rather than reproducing the full Tβ4 protein, the fragment isolates the sequence associated with actin binding, which is what makes it useful as a research reagent: it lets the actin-related signaling be studied without the rest of the parent molecule.

In laboratory models the research areas follow the parent protein's known biology — extracellular matrix and collagen remodeling, angiogenesis and vascular endpoints, and cell migration in epithelial systems. Smart and colleagues' 2007 work on progenitor mobilization remains a common reference point. At 4,963.5 g/mol (C₂₁₂H₃₅₀N₅₆O₇₈S) it is a mid-size peptide and is frequently studied alongside BPC-157 in comparative structural-recovery work.

Reconstitution and handling (research use)

Wholesale TB-500 ships lyophilized. For in-vitro use it is reconstituted with bacteriostatic or sterile water introduced slowly down the vial wall; at roughly 5 kDa it is large enough that vigorous agitation risks shear and foaming, so gentle swirling until the cake clears is the standard approach.

Lyophilized material is generally stored at -20°C protected from light, and reconstituted solution refrigerated at 2–8°C and used within the working window the study defines. Aliquoting before freezing avoids repeated freeze-thaw cycles. These notes cover general laboratory handling of a chemical reagent only — not human or veterinary use.

Wholesale sourcing notes

TB-500 is stocked wholesale in 5 mg and 10 mg presentations. Every lot is US-sourced and independently verified by third-party HPLC/MS for identity, purity, and quantitation, with a per-lot COA available as a paid add-on.

It is one of the more frequently ordered compounds in the recovery and structural category, and is commonly paired with BPC-157 — a BPC/TB-500 blend is stocked as a separate line for labs wanting both in a single vial. Volume pricing runs across the 100, 250, 500, and 1,000-vial bands under a 100-vial mix-and-match minimum.

Key Areas of Research

Structural: collagen, matrix, tendon/ligament
Vascular: angiogenesis, nitric oxide, remodeling
Epithelial: migration, signaling, matrix

References

Goldstein A.L. et al. (2005). Discovery of thymosins. Ann N Y Acad Sci 1042:1–8.
Smart N. et al. (2007). Thymosin beta-4 progenitor mobilization. Nature 445:177–182.

TB-500 — Frequently Asked Questions

What is TB-500?: TB-500 is a synthetic peptide fragment derived from thymosin beta-4, studied for its influence on matrix remodeling, angiogenesis, and molecular migration.
What is the CAS number for TB-500?: The CAS number for TB-500 is 77591-33-4. Its molecular formula is C₂₁₂H₃₅₀N₅₆O₇₈S (MW 4,963.5 g/mol).
What doses of TB-500 are available wholesale?: Wholesale Peptide Supply stocks TB-500 in 5mg, 10mg. Wholesale pricing is provided by quote based on order volume across 100–1,000 vials.
Is TB-500 third-party tested?: Yes. Every lot of TB-500 is tested by an independent third-party laboratory using HPLC/MS, and a per-lot Certificate of Analysis documenting identity and purity is available as a paid add-on.
Is TB-500 for human use?: No. TB-500 is sold strictly as a chemical reagent for in-vitro laboratory research and is not for human or veterinary use. Wholesale Peptide Supply is not a pharmacy or compounding facility.
How do I get wholesale pricing for TB-500?: Request a quote through our contact form or open a wholesale account. An account manager replies with volume pricing and lead times, typically within 10 minutes during business hours.
Can I order TB-500 in bulk?: Yes. TB-500 is available for bulk and wholesale orders, quoted by dose and volume, with the lower price earned per compound at 100 kits (1,000 vials). Submit the doses and quantities you need for a bulk quote; all material is sourced in the USA and third-party HPLC/MS tested.
Is TB-500 the same as thymosin beta-4?: No. Thymosin beta-4 (Tβ4) is the full parent protein, first isolated in the 1960s. TB-500 is a shorter synthetic fragment corresponding to its active actin-binding region, synthesized so that region can be studied on its own. They are distinct materials and are not interchangeable in laboratory models.
What doses of TB-500 are available wholesale?: TB-500 is stocked in 5 mg and 10 mg vials under CAS 77591-33-4, each with per-lot HPLC/MS verification. A BPC/TB-500 blend is also stocked as a separate catalog line for combined structural research.

Research Use Only

All products are intended solely for laboratory research purposes and are not for human or animal consumption. Must be handled by qualified professionals.