Research Use Only. 5-Amino-1-MQ is sold as a chemical reagent for in-vitro laboratory research. It is not a drug, supplement, or compounded preparation, and it is not for human or veterinary use. Wholesale Peptide Supply is not a pharmacy or compounding facility under 503A or 503B.
5-Amino-1-MQ
5-Amino-1-MQ is a small molecule inhibitor of nicotinamide N-methyltransferase (NNMT), affecting NAD+ and SAM availability and methylation capacity.
Wholesale Catalog
Available Doses
Wholesale pricing for 5-Amino-1-MQ is provided by quote based on dose and order volume. Tell us what you need and your account manager will send a personalized quote — typically within 10 minutes during business hours.
Overview
5-Amino-1-MQ is a small molecule inhibitor of nicotinamide N-methyltransferase (NNMT), affecting NAD+ and SAM availability and methylation capacity.
History
Developed as a selective, cell-permeable NNMT inhibitor; early studies showed dose-dependent effects on fat mass and metabolic markers.
Key Areas of Research
- NNMT inhibition, NAD+ pathway
- Adipogenesis, lipid signaling
- SAM dynamics, one-carbon metabolism
References
- Ruf S. et al. (2019). J Med Chem 62(4):2060–2072.
- Neelakantan H. et al. (2018). Biochem Pharmacol 147:179–190.
Research Use Only
All products are intended solely for laboratory research purposes and are not for human or animal consumption. Must be handled by qualified professionals.
Related Compounds
Anti-Aging & Longevity
SS-31
SS-31 (Elamipretide) is a mitochondria-targeting tetrapeptide that selectively accumulates at the inner mitochondrial membrane and interacts with cardiolipin. Studied for effects on cristae architecture, ATP synthesis, and ROS modulation.
View details →Anti-Aging & Longevity
Epithalon
Epithalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide derived from epithalamin, studied for telomere dynamics, pineal gland regulation, and circadian signaling.
View details →Anti-Aging & Longevity
NAD+
NAD⁺ is a coenzyme central to redox reactions and bioenergetic processes, studied for its role in mitochondrial function, sirtuin activation, and PARP signaling.
View details →