What is the CAS number for SS-31?

The CAS number for SS-31 is 736992-21-5. Its molecular formula is C₃₂H₄₉N₉O₆ · 4HCl (MW 640.80 g/mol (free base)).

What doses of SS-31 are available wholesale?

Wholesale Peptide Supply stocks SS-31 in 10mg, 50mg. Wholesale pricing is provided by quote based on order volume across 100–1,000 vials.

Is SS-31 third-party tested?

Yes. Every lot of SS-31 is tested by an independent third-party laboratory using HPLC/MS, and a per-lot Certificate of Analysis documenting identity and purity is available as a paid add-on.

Is SS-31 for human use?

No. SS-31 is sold strictly as a chemical reagent for in-vitro laboratory research and is not for human or veterinary use. Wholesale Peptide Supply is not a pharmacy or compounding facility.

How do I get wholesale pricing for SS-31?

Request a quote through our contact form or open a wholesale account. An account manager replies with volume pricing and lead times, typically within 10 minutes during business hours.

Can I order SS-31 in bulk?

Yes. SS-31 is available for bulk and wholesale orders, quoted by dose and volume, with the lower price earned per compound at 100 kits (1,000 vials). Submit the doses and quantities you need for a bulk quote; all material is sourced in the USA and third-party HPLC/MS tested.

Why does the SS-31 molecular weight differ from the vial contents?

SS-31 is supplied as a tetrahydrochloride salt (C₃₂H₄₉N₉O₆ · 4HCl), while the quoted 640.80 g/mol is the free-base weight. For quantitative laboratory work, use the salt mass or the per-vial peptide content documented on the per-lot Certificate of Analysis rather than the free-base figure.

Is SS-31 the same compound as elamipretide?

Yes. SS-31 and elamipretide refer to the same mitochondria-targeting tetrapeptide, CAS 736992-21-5. It was the first compound in the Szeto-Schiller peptide class, developed at Weill Cornell Medicine in the early 2000s. It is supplied for laboratory research use only.

Research Use Only. SS-31 is sold as a chemical reagent for in-vitro laboratory research. It is not a drug, supplement, or compounded preparation, and it is not for human or veterinary use. Wholesale Peptide Supply is not a pharmacy or compounding facility under 503A or 503B.

Anti-Aging & LongevityCAS 736992-21-5

Wholesale SS-31 — Bulk Research Supply

Buy SS-31 wholesale and in bulk from a US-based research peptide supplier. Every lot is sourced in the USA and third-party third-party tested via HPLC/MS. Bulk SS-31 is quoted by dose and volume from a 100-vial mix-and-match minimum; volume pricing is earned per compound at 100 kits.

SS-31 (Elamipretide) is a mitochondria-targeting tetrapeptide that selectively accumulates at the inner mitochondrial membrane and interacts with cardiolipin. Studied for effects on cristae architecture, ATP synthesis, and ROS modulation.

Wholesale Catalog

Available Doses

Published per-vial wholesale pricing for SS-31. Sold in kits of 10 vials with a 100-vial order minimum you can mix and match across compounds; volume pricing applies at 1,000+ vials. Contact us for larger or custom-volume quotes — typically answered within 10 minutes during business hours.

SS-31 10mg

WPS2S10 · CAS 736992-21-5 · Anti-Aging & Longevity

$18.69/vial · under 100 kits · $14.95/vial · 100+ kits of this item

Sold in kits of 10 vials · 100-vial order minimum (mix & match across compounds) · 100+ kits of this item unlocks the lower price

Quantity

10 vials

1 kit

Request a custom quote

SS-31 50mg

WPS2S50 · CAS 736992-21-5 · Anti-Aging & Longevity

$74.75/vial · under 100 kits · $59.80/vial · 100+ kits of this item

Sold in kits of 10 vials · 100-vial order minimum (mix & match across compounds) · 100+ kits of this item unlocks the lower price

Quantity

10 vials

1 kit

Request a custom quote

Overview

History

Developed by Hazel Szeto and Peter Schiller at Weill Cornell Medicine in the early 2000s; first in the SS peptide class.

Structure and mechanism

SS-31 (elamipretide) is a tetrapeptide with an alternating aromatic-cationic motif, and that architecture is what gives it its defining property: it concentrates at the inner mitochondrial membrane without depending on the membrane potential that most mitochondrial probes rely on. Once there it associates with cardiolipin, the signature phospholipid of the inner membrane.

In preclinical laboratory models the research questions follow from that binding — how cardiolipin association affects cristae architecture, what happens to electron-transport efficiency and ATP synthesis when the membrane's lipid environment is stabilized, and how reactive oxygen species behave under ischemia-reperfusion conditions. It was the first compound in the SS (Szeto-Schiller) peptide class, developed at Weill Cornell in the early 2000s.

Reconstitution and handling (research use)

Wholesale SS-31 ships as a lyophilized tetrahydrochloride salt. One handling detail matters more here than with most peptides: the stated molecular weight of 640.80 g/mol is the free base, while the material in the vial is the 4HCl salt (C₃₂H₄₉N₉O₆ · 4HCl). Concentration calculations should use the salt mass for the weighed quantity, or the per-vial peptide content stated on the COA, rather than the free-base figure.

The compound is highly water-soluble and reconstitutes readily in bacteriostatic or sterile water. Lyophilized material is stored at -20°C protected from light; reconstituted solution is refrigerated at 2–8°C. These notes describe general laboratory handling of a chemical reagent only — not human or veterinary use.

Wholesale sourcing notes

SS-31 is stocked wholesale in 10 mg and 50 mg presentations, the 50 mg being the larger fill for labs running extended mitochondrial panels. Every lot is US-sourced and independently verified by third-party HPLC/MS for identity, purity, and quantitation, with a per-lot COA available as a paid add-on.

Because the material is supplied as a salt, the per-lot COA is worth adding for quantitative work — it documents the actual peptide content rather than the gross fill weight. Volume pricing spans the 100, 250, 500, and 1,000-vial bands under a 100-vial mix-and-match minimum.

Certificates of Analysis

Every lot of SS-31 is tested by an independent third-party laboratory using HPLC/MS. 7 certificates are on file below — open any one to read the full report.

Lot	Dose	Tested
100089-0956	10mg	2026-08-20
100089-0957	50mg	2026-08-20
100057-0616	50mg	2026-08-05
100032-0307	10mg	2026-07-29
100032-0328	10mg	2026-07-29
100032-0309	50mg	2026-07-29
2606AFL1031.3699	10mg	On file

Key Areas of Research

Cardiolipin interaction, cristae remodeling
ATP synthesis dynamics
ROS modulation, ischemia-reperfusion

References

Szeto H.H. (2014). Br J Pharmacol 171(8):2029–2050.
Birk A.V. et al. (2013). J Am Soc Nephrol 24(8):1250–1261.

SS-31 — Frequently Asked Questions

What is SS-31?: SS-31 (Elamipretide) is a mitochondria-targeting tetrapeptide that selectively accumulates at the inner mitochondrial membrane and interacts with cardiolipin. Studied for effects on cristae architecture, ATP synthesis, and ROS modulation.
What is the CAS number for SS-31?: The CAS number for SS-31 is 736992-21-5. Its molecular formula is C₃₂H₄₉N₉O₆ · 4HCl (MW 640.80 g/mol (free base)).
What doses of SS-31 are available wholesale?: Wholesale Peptide Supply stocks SS-31 in 10mg, 50mg. Wholesale pricing is provided by quote based on order volume across 100–1,000 vials.
Is SS-31 third-party tested?: Yes. Every lot of SS-31 is tested by an independent third-party laboratory using HPLC/MS, and a per-lot Certificate of Analysis documenting identity and purity is available as a paid add-on.
Is SS-31 for human use?: No. SS-31 is sold strictly as a chemical reagent for in-vitro laboratory research and is not for human or veterinary use. Wholesale Peptide Supply is not a pharmacy or compounding facility.
How do I get wholesale pricing for SS-31?: Request a quote through our contact form or open a wholesale account. An account manager replies with volume pricing and lead times, typically within 10 minutes during business hours.
Can I order SS-31 in bulk?: Yes. SS-31 is available for bulk and wholesale orders, quoted by dose and volume, with the lower price earned per compound at 100 kits (1,000 vials). Submit the doses and quantities you need for a bulk quote; all material is sourced in the USA and third-party HPLC/MS tested.
Why does the SS-31 molecular weight differ from the vial contents?: SS-31 is supplied as a tetrahydrochloride salt (C₃₂H₄₉N₉O₆ · 4HCl), while the quoted 640.80 g/mol is the free-base weight. For quantitative laboratory work, use the salt mass or the per-vial peptide content documented on the per-lot Certificate of Analysis rather than the free-base figure.
Is SS-31 the same compound as elamipretide?: Yes. SS-31 and elamipretide refer to the same mitochondria-targeting tetrapeptide, CAS 736992-21-5. It was the first compound in the Szeto-Schiller peptide class, developed at Weill Cornell Medicine in the early 2000s. It is supplied for laboratory research use only.

Research Use Only

All products are intended solely for laboratory research purposes and are not for human or animal consumption. Must be handled by qualified professionals.