IGF-LR3
IGF-LR3 (Long Arg3 IGF-1) is a synthetic IGF-1 analog with reduced IGFBP binding and significantly extended half-life, used to investigate IGF-1 receptor-mediated signaling and metabolic regulation.
Wholesale Pricing
Available Doses & Tiered Pricing
IGF-LR3 1mg
Save 18%- 50 vials$34.00 / vial
- 100 vials$32.00 / vial
- 250 vials$30.00 / vial
- 500 vials★ Best Value$28.00 / vial
Overview
IGF-LR3 (Long Arg3 IGF-1) is a synthetic IGF-1 analog with reduced IGFBP binding and significantly extended half-life, used to investigate IGF-1 receptor-mediated signaling and metabolic regulation.
History
Developed in the 1990s; the N-terminal extension and Arg3 substitution synergistically reduce IGFBP binding while maintaining receptor affinity.
Key Areas of Research
- IGF-1 receptor activation
- PI3K/Akt/mTOR cascades
- Cellular proliferation and survival
References
- Clemmons D.R. (2007). Nat Rev Drug Discov 6(10):821–833.
- Rinderknecht E., Humbel R.E. (1978). J Biol Chem 253(8):2769–2776.
Research Use Only
All products are intended solely for laboratory research purposes and are not for human or animal consumption. Must be handled by qualified professionals.
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