Research Use Only. IGF-LR3 is sold as a chemical reagent for in-vitro laboratory research. It is not a drug, supplement, or compounded preparation, and it is not for human or veterinary use. Wholesale Peptide Supply is not a pharmacy or compounding facility under 503A or 503B.

Growth HormoneCAS 946870-92-4

IGF-LR3

IGF-LR3 (Long Arg3 IGF-1) is a synthetic IGF-1 analog with reduced IGFBP binding and significantly extended half-life, used to investigate IGF-1 receptor-mediated signaling and metabolic regulation.

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IGF-LR3 1mg

CAS 946870-92-4 · Growth Hormone

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Overview

IGF-LR3 (Long Arg3 IGF-1) is a synthetic IGF-1 analog with reduced IGFBP binding and significantly extended half-life, used to investigate IGF-1 receptor-mediated signaling and metabolic regulation.

History

Developed in the 1990s; the N-terminal extension and Arg3 substitution synergistically reduce IGFBP binding while maintaining receptor affinity.

Key Areas of Research

  • IGF-1 receptor activation
  • PI3K/Akt/mTOR cascades
  • Cellular proliferation and survival

References

  1. Clemmons D.R. (2007). Nat Rev Drug Discov 6(10):821–833.
  2. Rinderknecht E., Humbel R.E. (1978). J Biol Chem 253(8):2769–2776.

Research Use Only

All products are intended solely for laboratory research purposes and are not for human or animal consumption. Must be handled by qualified professionals.

Related Compounds