Research Use Only. CJC-1295 (no DAC) is sold as a chemical reagent for in-vitro laboratory research. It is not a drug, supplement, or compounded preparation, and it is not for human or veterinary use. It must be handled by qualified professionals. Wholesale Peptide Supply is not a pharmacy or compounding facility under 503A or 503B.
Wholesale CJC-1295 (no DAC) — Bulk Research Supply
Buy CJC-1295 (no DAC) wholesale and in bulk from a US-based research peptide supplier. Every lot is sourced in the USA and third-party tested via HPLC/MS. Bulk CJC-1295 (no DAC) is quoted by dose and volume from a 100-vial mix-and-match minimum; volume pricing is earned per compound at 100 kits.
CJC-1295 without DAC — also called modified GRF (1-29) — is a GHRH analog carrying four amino acid substitutions that resist enzymatic cleavage, without the drug affinity complex that extends the DAC variant's half-life.
Wholesale Catalog
Available Doses
Published per-vial wholesale pricing for CJC-1295 (no DAC). Sold in kits of 10 vials with a 100-vial order minimum you can mix and match across compounds; volume pricing applies at 1,000+ vials. Contact us for larger or custom-volume quotes — typically answered within 10 minutes during business hours.
CJC-1295 (no DAC) 10mg50% off
WPSCND10 · CAS 863288-34-0 · Growth Hormone
$38.53$19.26/vial · 50% off at any volumeWhile supplies last
Discontinued — limited to stock on hand. Once it's gone, it's gone. Sold in kits of 10 vials · 100-vial order minimum (mix & match across compounds).
Overview
CJC-1295 without DAC — also called modified GRF (1-29) — is a GHRH analog carrying four amino acid substitutions that resist enzymatic cleavage, without the drug affinity complex that extends the DAC variant's half-life.
History
Built on the GRF (1-29) fragment that also underlies sermorelin, with substitutions at positions 2, 8, 15 and 27 to slow degradation. Removing the DAC linker yields a short-acting analog studied as a pulsatile counterpart to the DAC version.
Structure and mechanism
CJC-1295 without DAC — also catalogued in the literature as Mod-GRF (1-29) — is a modified analogue of the first 29 amino acids of growth-hormone-releasing factor, carrying four amino-acid substitutions that confer resistance to enzymatic degradation.\n\nWhat it does not carry is the Drug Affinity Complex. The DAC form of CJC-1295 adds a maleimidopropionic acid group that binds covalently to albumin and extends the compound's measurable presence in preclinical models from minutes to days; the no-DAC form omits it entirely and clears rapidly. The two share a backbone and a name and are otherwise different reagents, which is the single most common point of confusion when this compound is ordered.
Reconstitution and handling (research use)
CJC-1295 without DAC ships as a lyophilized powder in 10 mg vials. For in-vitro laboratory use it is reconstituted with bacteriostatic or sterile water at the volume needed to reach the assay's target concentration. Unlike the DAC form it carries no maleimide group, so it has no particular incompatibility with reducing agents in buffer.\n\nLyophilized material is stored at -20°C protected from light; reconstituted solution is refrigerated at 2-8°C. General reagent handling guidance only — not for human or veterinary use.
Wholesale sourcing notes
CJC-1295 without DAC is stocked in 10 mg vials and is the form used in the CJC/IPA no-DAC blend, which is how a large share of wholesale buyers order the CJC-plus-ipamorelin combination. Material is US-sourced and third-party HPLC/MS verified.\n\nBecause the market uses 'CJC-1295' loosely for both variants, the SKU and the Certificate of Analysis name the form explicitly on every order. A per-lot COA is included at no charge, issued in the name of Wholesale Peptide Supply.
Certificates of Analysis
2 certificates are on file for CJC-1295 (no DAC) — open any one to read the full report.
| Lot | Dose | Tested | Certificate |
|---|---|---|---|
| 100057-0598 | 10mg | 2026-08-05 | |
| 100057-0597 | 5mg | 2026-08-05 |
Key Areas of Research
- GHRH receptor binding and selectivity
- Pulsatile vs. sustained signaling profiles
- Comparative studies vs. CJC-1295 with DAC and sermorelin
- Enzymatic stability of substituted analogs
References
- Teichman S.L. et al. (2006). Prolonged stimulation of growth hormone and IGF-I secretion by CJC-1295. J Clin Endocrinol Metab, 91(3):799–805.
- Jetté L. et al. (2005). hGRF1-29-albumin bioconjugates. Endocrinology, 146(7):3052–3058.
CJC-1295 (no DAC) — Frequently Asked Questions
- What is CJC-1295 (no DAC)?
- CJC-1295 without DAC — also called modified GRF (1-29) — is a GHRH analog carrying four amino acid substitutions that resist enzymatic cleavage, without the drug affinity complex that extends the DAC variant's half-life.
- What is the CAS number for CJC-1295 (no DAC)?
- The CAS number for CJC-1295 (no DAC) is 863288-34-0. Its molecular formula is C₁₅₂H₂₅₂N₄₄O₄₂ (MW 3,367.9 g/mol).
- What doses of CJC-1295 (no DAC) are available wholesale?
- Wholesale Peptide Supply stocks CJC-1295 (no DAC) in 10mg. Wholesale pricing is provided by quote based on order volume across 100–1,000 vials.
- Is CJC-1295 (no DAC) third-party tested?
- Yes. Every lot of CJC-1295 (no DAC) is tested by an independent third-party laboratory using HPLC/MS, and a per-lot Certificate of Analysis documenting identity and purity is included with every order at no charge, issued in the name of Wholesale Peptide Supply.
- Is CJC-1295 (no DAC) for human use?
- No. CJC-1295 (no DAC) is sold strictly as a chemical reagent for in-vitro laboratory research and is not for human or veterinary use. Wholesale Peptide Supply is not a pharmacy or compounding facility.
- How do I get wholesale pricing for CJC-1295 (no DAC)?
- Request a quote through our contact form or open a wholesale account. An account manager replies with volume pricing and lead times, typically within 10 minutes during business hours.
- Can I order CJC-1295 (no DAC) in bulk?
- Yes. CJC-1295 (no DAC) is available for bulk and wholesale orders, quoted by dose and volume, with the lower price earned per compound at 100 kits (1,000 vials). Submit the doses and quantities you need for a bulk quote.
- Is CJC-1295 without DAC the same as Mod-GRF (1-29)?
- Yes — they are two names for the same compound: a modified GRF(1-29) analogue with four substitutions and no Drug Affinity Complex. The literature tends to use Mod-GRF (1-29); the wholesale market tends to say CJC-1295 no-DAC.
- Which form is used in the CJC/IPA blend?
- The no-DAC form. The CJC/IPA blend is stocked as a single pre-blended lyophilized preparation combining CJC-1295 without DAC and ipamorelin, which is how most wholesale buyers order that combination. All three items are also available individually.
Related Compounds
Growth Hormone
Tesamorelin
Tesamorelin is a synthetic analog of growth hormone releasing hormone built on the full 44-residue GHRH sequence, carrying an N-terminal trans-3-hexenoyl modification that resists enzymatic cleavage and extends the window of GHRH receptor engagement relative to native GHRH.
View details →Growth Hormone
Ipamorelin
Ipamorelin is a synthetic pentapeptide and selective secretagogue-type agonist with minimal off-target pathway interference, used to study endocrine signaling and somatotroph axis modulation.
View details →Growth Hormone
CJC-1295 w/DAC
CJC-1295 with DAC is a modified GHRH analog with prolonged half-life through albumin binding, enabling sustained somatotroph axis activation in experimental models.
View details →Growth Hormone
CJC/IPA No DAC Blend
Combines CJC-1295 No DAC with Ipamorelin to target two complementary signaling pathways. The No DAC variant maintains a shorter duration of action enabling pulsatile GH dynamics.
View details →Growth Hormone
IGF-LR3
IGF-LR3 (Long Arg3 IGF-1) is a synthetic IGF-1 analog with reduced IGFBP binding and significantly extended half-life, used to investigate IGF-1 receptor-mediated signaling and metabolic regulation.
View details →Growth Hormone
Thymosin Alpha 1
Thymosin Alpha 1 functions as a potent immunomodulator influencing signaling dynamics, cytokine expression, and immune pathway homeostasis.
View details →Growth Hormone
GHRP-2 Acetate
GHRP-2 (pralmorelin) is a synthetic hexapeptide growth hormone secretagogue with the sequence D-Ala-D-2Nal-Ala-Trp-D-Phe-Lys-NH₂, studied as a ghrelin receptor agonist in laboratory models.
View details →Growth Hormone
GHRP-6 Acetate
GHRP-6 is a synthetic hexapeptide growth hormone secretagogue with the sequence His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂. It was the first of the GHRP series to be widely characterized and remains a common reference compound in secretagogue research.
View details →