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Research Use Only. Semax is sold as a chemical reagent for in-vitro laboratory research, not for human or veterinary use.

Cognitive / NeuroCAS 80714-61-0

Wholesale Semax — Bulk Research Supply

Available sizes

In-stock orders ship same day when paid by 1 pm PT, Mon–Fri. Overnight available.

Buy Semax wholesale and in bulk from a US-based research peptide supplier. Every lot is sourced in the USA and third-party tested, with the lab and method on each lot's certificate. Bulk Semax is quoted by dose and volume from a 3-kit (30-vial) order minimum, mix and match across doses and compounds; lower prices are earned at 10 kits and again at 100 kits in the order, mix and match.

Semax is a synthetic heptapeptide derived from ACTH 4-10 with a C-terminal Pro-Gly-Pro extension, studied for neuronal signaling, CNS pathway dynamics, and stress responses.

Wholesale Semax 10mg lyophilized vial — Wholesale Peptide Supply
Semax 10mg lyophilized vial as supplied. Labeling is customizable for private-label orders.

Wholesale Catalog

Available Doses

Published per-vial wholesale pricing for Semax. Sold in kits of 10 vials with a 3-kit (30-vial) order minimum, mix and match across doses and compounds; lower prices apply at 10 kits and at 1,000+ vials in the order. Contact us for larger or custom-volume quotes — answered the same day. Urgent? Text or call (714) 625-9215 — you’ll reach a real person in the United States, not a chatbot or an overseas call center.

Semax 10mg

WPSSX10 · CAS 80714-61-0 · Cognitive / Neuro

1–9 kits
$15.81/vial$14.23 paying by card
10–99 kits
$12.65/vial$11.39 paying by card
100+ kits
$10.12/vial$9.11 paying by card

10% off with card Every product, every volume band — taken off at checkout when you choose card.

Sold in kits of 10 vials · 3-kit order minimum, mix and match · price set by the total kits in your order (BAC water not counted)

Quantity
3 kits
Request a custom quote

Questions? Text a rep or call (714) 625-9215 — a real person in the US answers.

Overview

Semax is a synthetic heptapeptide derived from ACTH 4-10 with a C-terminal Pro-Gly-Pro extension, studied for neuronal signaling, CNS pathway dynamics, and stress responses.

History

Developed in Russia in the 1980s–1990s as a stable, non-hormonal peptide for CNS research.

Structure and mechanism

Semax is a synthetic heptapeptide built from the ACTH (4-10) fragment with a C-terminal Pro-Gly-Pro extension. The parent fragment carries no hormonal activity, and the tripeptide tail is a stability device — the Pro-Gly-Pro motif substantially slows enzymatic degradation relative to the bare fragment, which is why the modified peptide is usable as a research reagent where ACTH (4-10) alone is not.

In laboratory models Semax is studied for neuronal signaling dynamics, with recurring interest in BDNF and neurotrophin expression, synaptic plasticity and memory-pathway markers, and behavior under oxidative and stress conditions. It was developed in Russia through the 1980s and 1990s specifically as a stable non-hormonal peptide for CNS research, and at ~813 g/mol it sits at the small, readily handled end of the catalog.

Reconstitution and handling (research use)

Wholesale Semax ships lyophilized and is straightforward to work with: at heptapeptide scale it dissolves quickly in bacteriostatic or sterile water without the shear and foaming precautions larger peptides require. The methionine residue implied by the formula's sulfur is the main oxidation-sensitive point, so limiting headspace and prolonged room-temperature exposure after reconstitution is worthwhile.

Lyophilized powder is generally held at -20°C protected from light; reconstituted solution is refrigerated at 2–8°C and used within the protocol's window. These notes cover general laboratory handling of a chemical reagent only — not human or veterinary use.

Wholesale sourcing notes

Semax is stocked wholesale in a 10 mg presentation. Every lot is US-sourced and third-party verified for identity, purity, and quantitation, with a per-lot COA included in every order.

It is most often ordered alongside Selank — the two are the standard pairing in comparative CNS peptide work, and a Semax/Selank blend is stocked as a separate line for labs that want both in one vial. Pricing is in three bands set by the order's total kits — 1–9 kits, 10–99 kits and 100+ kits (1,000 vials), mix and match — from a 3-kit (30-vial) order minimum, mix and match across doses and compounds.

Certificates of Analysis

5 certificates are on file for Semax — open any one to read the full report.

Lot / LabDoseTestedPurityCertificate
DPS-7737418Horizon AnalyticalUPLC/MS10mg2026-10-0399.37%Endotoxin <0.05 EU/mL
100089-0952Optiq Health LabsRP-HPLC / LC-MS10mg2026-08-20—
100089-0953Optiq Health LabsRP-HPLC / LC-MS30mg2026-08-20—
100032-0322Optiq Health LabsRP-HPLC / LC-MS10mg2026-07-29—
100031-0287Optiq Health LabsRP-HPLC10mg2026-07-27—

Key Areas of Research

  • Neuronal signaling, BDNF modulation
  • Synaptic plasticity, memory pathways
  • Stress and oxidative pathways

References

  1. Ashmarin I.P. et al. (1997). Zh Vyssh Nerv Deiat 47(2):419–426.
  2. Inozemtsev A.N. et al. (2008). Eksp Klin Farmakol 71(2):3–7.

Semax — Frequently Asked Questions

What is Semax?
Semax is a synthetic heptapeptide derived from ACTH 4-10 with a C-terminal Pro-Gly-Pro extension, studied for neuronal signaling, CNS pathway dynamics, and stress responses.
What is the CAS number for Semax?
The CAS number for Semax is 80714-61-0. Its molecular formula is C₃₇H₅₁N₉O₁₀S (MW ~813 g/mol).
What doses of Semax are available wholesale?
Wholesale Peptide Supply stocks Semax in 10mg. Wholesale pricing is provided by quote based on order volume, from a 3-kit (30-vial) order minimum, mix and match across doses and compounds.
Is Semax third-party tested?
Yes. Every lot of Semax is tested by an independent third-party laboratory, and a per-lot Certificate of Analysis documenting identity and purity is included with every order at no charge, issued in the name of Wholesale Peptide Supply. The most recent published lot, DPS-7737418 (10mg), was tested by Horizon Analytical on 3 October 2026 by UPLC/MS: purity 99.37%, endotoxin <0.05 EU/mL. Every lot on file is listed with its certificate on this page.
Is Semax for human use?
No. Semax is sold strictly as a chemical reagent for in-vitro laboratory research and is not for human or veterinary use. Wholesale Peptide Supply is not a pharmacy or compounding facility.
How do I get wholesale pricing for Semax?
Request a quote through our contact form or open a wholesale account. An account manager replies with volume pricing and lead times the same day. For anything urgent, text or call (714) 625-9215 to reach a real person in the US.
Can I order Semax in bulk?
Yes. Semax is available for bulk and wholesale orders, quoted by dose and volume, from a 3-kit (30-vial) order minimum, mix and match across doses and compounds, with lower prices at 10 kits and at 100 kits (1,000 vials) in the order. Submit the doses and quantities you need for a bulk quote.
What is the difference between Semax and Selank?
They are structurally unrelated heptapeptides with different origins. Semax derives from the ACTH (4-10) fragment with a Pro-Gly-Pro extension and is studied for neurotrophin and synaptic-plasticity pathways. Selank is an analog of the immune peptide tuftsin and is studied for GABAergic and cytokine signaling. Both came out of Russian research institutes; they are not interchangeable in laboratory models.
What doses of Semax are stocked wholesale?
Semax is stocked in 10 mg vials under CAS 80714-61-0 with per-lot third-party verification. A Semax / Selank blend is also stocked as a separate catalog line.

Related Compounds

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