Research Use Only. Semax is sold as a chemical reagent for in-vitro laboratory research. It is not a drug, supplement, or compounded preparation, and it is not for human or veterinary use. Wholesale Peptide Supply is not a pharmacy or compounding facility under 503A or 503B.
Wholesale Semax — Bulk Research Supply
Buy Semax wholesale and in bulk from a US-based research peptide supplier. Every lot is sourced in the USA and third-party third-party tested via HPLC/MS. Bulk Semax is quoted by dose and volume from a 100-vial mix-and-match minimum; volume pricing is earned per compound at 100 kits.
Semax is a synthetic heptapeptide derived from ACTH 4-10 with a C-terminal Pro-Gly-Pro extension, studied for neuronal signaling, CNS pathway dynamics, and stress responses.
Wholesale Catalog
Available Doses
Published per-vial wholesale pricing for Semax. Sold in kits of 10 vials with a 100-vial order minimum you can mix and match across compounds; volume pricing applies at 1,000+ vials. Contact us for larger or custom-volume quotes — typically answered within 10 minutes during business hours.
Semax 10mg
WPSSX10 · CAS 80714-61-0 · Cognitive / Neuro
$12.65/vial · under 100 kits · $10.12/vial · 100+ kits of this item
Sold in kits of 10 vials · 100-vial order minimum (mix & match across compounds) · 100+ kits of this item unlocks the lower price
Semax 30mg
WPSSX30 · CAS 80714-61-0 · Cognitive / Neuro
$34.79/vial · under 100 kits · $27.83/vial · 100+ kits of this item
Sold in kits of 10 vials · 100-vial order minimum (mix & match across compounds) · 100+ kits of this item unlocks the lower price
Overview
Semax is a synthetic heptapeptide derived from ACTH 4-10 with a C-terminal Pro-Gly-Pro extension, studied for neuronal signaling, CNS pathway dynamics, and stress responses.
History
Developed in Russia in the 1980s–1990s as a stable, non-hormonal peptide for CNS research.
Structure and mechanism
Semax is a synthetic heptapeptide built from the ACTH (4-10) fragment with a C-terminal Pro-Gly-Pro extension. The parent fragment carries no hormonal activity, and the tripeptide tail is a stability device — the Pro-Gly-Pro motif substantially slows enzymatic degradation relative to the bare fragment, which is why the modified peptide is usable as a research reagent where ACTH (4-10) alone is not.
In laboratory models Semax is studied for neuronal signaling dynamics, with recurring interest in BDNF and neurotrophin expression, synaptic plasticity and memory-pathway markers, and behavior under oxidative and stress conditions. It was developed in Russia through the 1980s and 1990s specifically as a stable non-hormonal peptide for CNS research, and at ~813 g/mol it sits at the small, readily handled end of the catalog.
Reconstitution and handling (research use)
Wholesale Semax ships lyophilized and is straightforward to work with: at heptapeptide scale it dissolves quickly in bacteriostatic or sterile water without the shear and foaming precautions larger peptides require. The methionine residue implied by the formula's sulfur is the main oxidation-sensitive point, so limiting headspace and prolonged room-temperature exposure after reconstitution is worthwhile.
Lyophilized powder is generally held at -20°C protected from light; reconstituted solution is refrigerated at 2–8°C and used within the protocol's window. These notes cover general laboratory handling of a chemical reagent only — not human or veterinary use.
Wholesale sourcing notes
Semax is stocked wholesale in 10 mg and 30 mg presentations. Every lot is US-sourced and third-party verified by HPLC/MS for identity, purity, and quantitation, with a per-lot COA available as a paid add-on.
It is most often ordered alongside Selank — the two are the standard pairing in comparative CNS peptide work, and a Semax/Selank blend is stocked as a separate line for labs that want both in one vial. Volume pricing runs across the 100, 250, 500, and 1,000-vial bands under a 100-vial mix-and-match minimum.
Certificates of Analysis
Every lot of Semax is tested by an independent third-party laboratory using HPLC/MS. 4 certificates are on file below — open any one to read the full report.
| Lot | Dose | Tested | Certificate |
|---|---|---|---|
| 100089-0952 | 10mg | 2026-08-20 | |
| 100089-0953 | 30mg | 2026-08-20 | |
| 100032-0322 | 10mg | 2026-07-29 | |
| 100031-0287 | 10mg | 2026-07-27 |
Key Areas of Research
- Neuronal signaling, BDNF modulation
- Synaptic plasticity, memory pathways
- Stress and oxidative pathways
References
- Ashmarin I.P. et al. (1997). Zh Vyssh Nerv Deiat 47(2):419–426.
- Inozemtsev A.N. et al. (2008). Eksp Klin Farmakol 71(2):3–7.
Semax — Frequently Asked Questions
- What is Semax?
- Semax is a synthetic heptapeptide derived from ACTH 4-10 with a C-terminal Pro-Gly-Pro extension, studied for neuronal signaling, CNS pathway dynamics, and stress responses.
- What is the CAS number for Semax?
- The CAS number for Semax is 80714-61-0. Its molecular formula is C₃₇H₅₁N₉O₁₀S (MW ~813 g/mol).
- What doses of Semax are available wholesale?
- Wholesale Peptide Supply stocks Semax in 10mg, 30mg. Wholesale pricing is provided by quote based on order volume across 100–1,000 vials.
- Is Semax third-party tested?
- Yes. Every lot of Semax is tested by an independent third-party laboratory using HPLC/MS, and a per-lot Certificate of Analysis documenting identity and purity is available as a paid add-on.
- Is Semax for human use?
- No. Semax is sold strictly as a chemical reagent for in-vitro laboratory research and is not for human or veterinary use. Wholesale Peptide Supply is not a pharmacy or compounding facility.
- How do I get wholesale pricing for Semax?
- Request a quote through our contact form or open a wholesale account. An account manager replies with volume pricing and lead times, typically within 10 minutes during business hours.
- Can I order Semax in bulk?
- Yes. Semax is available for bulk and wholesale orders, quoted by dose and volume, with the lower price earned per compound at 100 kits (1,000 vials). Submit the doses and quantities you need for a bulk quote; all material is sourced in the USA and third-party HPLC/MS tested.
- What is the difference between Semax and Selank?
- They are structurally unrelated heptapeptides with different origins. Semax derives from the ACTH (4-10) fragment with a Pro-Gly-Pro extension and is studied for neurotrophin and synaptic-plasticity pathways. Selank is an analog of the immune peptide tuftsin and is studied for GABAergic and cytokine signaling. Both came out of Russian research institutes; they are not interchangeable in laboratory models.
- What doses of Semax are stocked wholesale?
- Semax is stocked in 10 mg and 30 mg vials, both under CAS 80714-61-0 with per-lot HPLC/MS verification. A Semax / Selank blend is also stocked as a separate catalog line.
Research Use Only
All products are intended solely for laboratory research purposes and are not for human or animal consumption. Must be handled by qualified professionals.
Related Compounds
Cognitive / Neuro
Selank
Selank is a synthetic heptapeptide analog of tuftsin studied for neurotransmitter signaling, stress response, and immune signaling.
View details →Cognitive / Neuro
DSIP
DSIP is a small amphiphilic nonapeptide with effects on circadian signaling and neuroendocrine regulation in experimental models.
View details →Cognitive / Neuro
Adamax
Adamax is a synthetic analog of the Semax peptide backbone, modified with N-terminal acetylation and a C-terminal adamantyl group. It is studied in laboratory models of peptide-mediated neurosignaling and neurotrophic pathway modulation.
View details →Cognitive / Neuro
Dihexa
Dihexa is a small-molecule angiotensin IV analog studied in laboratory models of hepatocyte growth factor / c-Met signaling and synaptic pathway activity.
View details →Cognitive / Neuro
Pinealon
Pinealon is the synthetic tripeptide Glu-Asp-Arg (EDR), one of the short peptide bioregulators developed in Russian gerontology research. It is studied in laboratory models of neuronal signaling and oxidative stress response.
View details →Cognitive / Neuro
Semax Liquid Spray
Semax supplied as an atomized solution in a metered spray bottle. A synthetic ACTH(4–10) analog studied for neurotrophic signalling.
View details →Cognitive / Neuro
Selank Liquid Spray
Selank supplied as an atomized solution in a metered spray bottle. A synthetic tuftsin analog studied for neuroimmune signalling.
View details →Cognitive / Neuro
DSIP Liquid Spray
Delta sleep-inducing peptide supplied as an atomized solution in a metered spray bottle — a nonapeptide studied for neuroendocrine signalling.
View details →