Research Use Only. KPV is sold as a chemical reagent for in-vitro laboratory research, not for human or veterinary use. It is not a drug, supplement, or compounded preparation. It must be handled by qualified professionals. Wholesale Peptide Supply is not a pharmacy or compounding facility under 503A or 503B.
Wholesale KPV — Bulk Research Supply
Available sizes
In-stock orders ship same day when paid by 1 pm PT, Mon–Fri. Overnight available.
Buy KPV wholesale and in bulk from a US-based research peptide supplier. Every lot is sourced in the USA and third-party tested, with the lab and method on each lot's certificate. Bulk KPV is quoted by dose and volume from a 3-kit (30-vial) order minimum, mix and match across doses and compounds; lower prices are earned at 10 kits and again at 100 kits in the order, mix and match.
KPV is a small tripeptide derived from the C-terminus of α-MSH studied for cytokine signaling, NF-κB modulation, and epithelial barrier dynamics.
Wholesale Catalog
Available Doses
Published per-vial wholesale pricing for KPV. Sold in kits of 10 vials with a 3-kit (30-vial) order minimum, mix and match across doses and compounds; lower prices apply at 10 kits and at 1,000+ vials in the order. Contact us for larger or custom-volume quotes — answered the same day. Urgent? Text or call (714) 625-9215 — you’ll reach a real person in the United States, not a chatbot or an overseas call center.
KPV 10mg
WPSKPV10 · CAS 67727-97-3 · Immune & Inflammatory
- 1–9 kits
- $22.64/vial$20.38 paying by card
- 10–99 kits
- $18.12/vial$16.30 paying by card
- 100+ kits
- $14.49/vial$13.04 paying by card
10% off with card Every product, every volume band — taken off at checkout when you choose card.
Sold in kits of 10 vials · 3-kit order minimum, mix and match · price set by the total kits in your order (BAC water not counted)
Questions? Text a rep or call (714) 625-9215 — a real person in the US answers.
Overview
KPV is a small tripeptide derived from the C-terminus of α-MSH studied for cytokine signaling, NF-κB modulation, and epithelial barrier dynamics.
History
Cytokine-modulating properties first identified in the late 1980s; PepT1-mediated uptake elucidated by Dalmasso et al. (2008).
Structure and mechanism
KPV is a tripeptide — lysine-proline-valine — corresponding to the C-terminal three residues of alpha-melanocyte-stimulating hormone. At three amino acids it is one of the smallest compounds in the catalog, with a molecular weight well under 400 g/mol, and its size is the defining practical characteristic: it behaves in solution far more like a small molecule than like the 15- to 40-residue peptides it sits alongside.
In preclinical work KPV is studied chiefly in inflammatory-signaling models, where interest centres on the observation that the tripeptide fragment retains activity in certain assays without the melanocortin-receptor binding associated with the full alpha-MSH sequence. It is frequently investigated in parallel with the full-length peptide for exactly that comparison.
Reconstitution and handling (research use)
KPV is supplied lyophilized in 10 mg vials. It reconstitutes readily in sterile or bacteriostatic water and, being a short and relatively robust tripeptide, tolerates handling that longer peptides in the catalog would not. Surface adsorption at very low working concentrations is still worth accounting for.
Lyophilized material is stored at -20°C protected from light; reconstituted solution is refrigerated at 2-8°C and used within the study's defined window. These are general laboratory notes for a chemical reagent, not human or veterinary use instructions.
Wholesale sourcing notes
KPV sits in the immune and inflammatory category and is commonly ordered alongside Thymosin Alpha-1 and LL-37 by buyers assembling an immune-signaling panel. It is stocked in 10 mg vials, sourced in the USA and independently verified by a third-party lab for identity, purity and quantitation.
Short peptides are cheap to synthesize and correspondingly easy to under-purify, which makes the HPLC trace on the Certificate of Analysis the thing worth checking on this compound. A per-lot COA is included with every order at no charge.
Also in this research area
If you stock KPV, see also LL-37. Each page lists its sizes and per-vial pricing.
Certificates of Analysis
2 certificates are on file for KPV — open any one to read the full report.
| Lot / Lab | Dose | Tested | Purity | Certificate |
|---|---|---|---|---|
| 20261008Optiq Health LabsRP-HPLC / LAL | 10mg | 2026-10-08 | 99.8%Endotoxin Pass (≤0.05 EU/mg) | |
| 100057-0609Optiq Health LabsRP-HPLC / LC-MS | 10mg | 2026-08-05 | — |
Key Areas of Research
- NF-κB pathway, TNF-α/IL-1β/IL-6/IL-8 regulation
- Tight junction regulation
- Mucosal inflammation models
References
- Dalmasso G. et al. (2008). Peptides 29(10):1875–1882.
- Hiltz M.E., Lipton J.M. (1989). FASEB J 3(11):2282–2284.
KPV — Frequently Asked Questions
- What is KPV?
- KPV is a small tripeptide derived from the C-terminus of α-MSH studied for cytokine signaling, NF-κB modulation, and epithelial barrier dynamics.
- What is the CAS number for KPV?
- The CAS number for KPV is 67727-97-3. Its molecular formula is C₁₆H₂₈N₆O₅ (MW 388.4 g/mol).
- What doses of KPV are available wholesale?
- Wholesale Peptide Supply stocks KPV in 10mg. Wholesale pricing is provided by quote based on order volume, from a 3-kit (30-vial) order minimum, mix and match across doses and compounds.
- Is KPV third-party tested?
- Yes. Every lot of KPV is tested by an independent third-party laboratory, and a per-lot Certificate of Analysis documenting identity and purity is included with every order at no charge, issued in the name of Wholesale Peptide Supply. The most recent published lot, 20261008 (10mg), was tested by Optiq Health Labs on 8 October 2026 by RP-HPLC / LAL: purity 99.8%, endotoxin Pass (≤0.05 EU/mg). Every lot on file is listed with its certificate on this page.
- Is KPV for human use?
- No. KPV is sold strictly as a chemical reagent for in-vitro laboratory research and is not for human or veterinary use. Wholesale Peptide Supply is not a pharmacy or compounding facility.
- How do I get wholesale pricing for KPV?
- Request a quote through our contact form or open a wholesale account. An account manager replies with volume pricing and lead times the same day. For anything urgent, text or call (714) 625-9215 to reach a real person in the US.
- Can I order KPV in bulk?
- Yes. KPV is available for bulk and wholesale orders, quoted by dose and volume, from a 3-kit (30-vial) order minimum, mix and match across doses and compounds, with lower prices at 10 kits and at 100 kits (1,000 vials) in the order. Submit the doses and quantities you need for a bulk quote.
- What is KPV derived from?
- KPV is the C-terminal tripeptide fragment — lysine-proline-valine — of alpha-melanocyte-stimulating hormone. It is studied in preclinical inflammatory-signaling models, frequently in parallel with the full-length alpha-MSH sequence for comparison.
- Is KPV a peptide or a small molecule?
- It is formally a peptide — three amino acids joined by peptide bonds — but at under 400 g/mol it behaves in solution much more like a small molecule than like the longer peptides in the catalog. That affects solubility and handling, and it is one of the more forgiving reagents in the range.
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