Immune & InflammatoryCAS 67727-97-3

KPV

KPV is a small tripeptide derived from the C-terminus of α-MSH studied for cytokine signaling, NF-κB modulation, and epithelial barrier dynamics.

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KPV 10mg

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Overview

KPV is a small tripeptide derived from the C-terminus of α-MSH studied for cytokine signaling, NF-κB modulation, and epithelial barrier dynamics.

History

Cytokine-modulating properties first identified in the late 1980s; PepT1-mediated uptake elucidated by Dalmasso et al. (2008).

Key Areas of Research

  • NF-κB pathway, TNF-α/IL-1β/IL-6/IL-8 regulation
  • Tight junction regulation
  • Mucosal inflammation models

References

  1. Dalmasso G. et al. (2008). Peptides 29(10):1875–1882.
  2. Hiltz M.E., Lipton J.M. (1989). FASEB J 3(11):2282–2284.

Research Use Only

All products are intended solely for laboratory research purposes and are not for human or animal consumption. Must be handled by qualified professionals.