Research Use Only. Kisspeptin-10 is sold as a chemical reagent for in-vitro laboratory research. It is not a drug, supplement, or compounded preparation, and it is not for human or veterinary use. It must be handled by qualified professionals. Wholesale Peptide Supply is not a pharmacy or compounding facility under 503A or 503B.
Wholesale Kisspeptin-10 — Bulk Research Supply
Buy Kisspeptin-10 wholesale and in bulk from a US-based research peptide supplier. Every lot is sourced in the USA and third-party tested via HPLC/MS. Bulk Kisspeptin-10 is quoted by dose and volume from a 100-vial mix-and-match minimum; volume pricing is earned per compound at 100 kits.
Kisspeptin-10 is the decapeptide Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂, corresponding to the bioactive C-terminal residues 45-54 of metastin. It is studied as a KISS1R (GPR54) agonist in laboratory models of neuroendocrine signaling.
Wholesale Catalog
Available Doses
Published per-vial wholesale pricing for Kisspeptin-10. Sold in kits of 10 vials with a 100-vial order minimum you can mix and match across compounds; volume pricing applies at 1,000+ vials. Contact us for larger or custom-volume quotes — typically answered within 10 minutes during business hours.
Kisspeptin-10 10mg
WPSKIS10 · CAS 374675-21-5 · Melanocortin
$15.24/vial · under 100 kits · $12.19/vial · 100+ kits of this item
Sold in kits of 10 vials · 100-vial order minimum (mix & match across compounds) · 100+ kits of this item unlocks the lower price
Overview
Kisspeptin-10 is the decapeptide Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂, corresponding to the bioactive C-terminal residues 45-54 of metastin. It is studied as a KISS1R (GPR54) agonist in laboratory models of neuroendocrine signaling.
History
The KISS1 gene was first characterized as a metastasis suppressor, and its peptide products were later identified as the endogenous ligands of GPR54, establishing the kisspeptin system as an upstream regulator in reproductive neuroendocrinology.
Where Kisspeptin-10 sits in the neuroendocrine cascade
Kisspeptin-10 is the decapeptide Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂, corresponding to residues 45-54 of metastin — the bioactive C-terminal fragment of the full KISS1 gene product.
Its research value comes largely from where it acts in the sequence of events rather than from the receptor alone. Signalling through KISS1R (GPR54) sits upstream of GnRH release, which in turn sits upstream of the gonadotropins. That puts Kisspeptin-10 at a different level of the same axis that HCG and HMG are used to probe further down.
So a model choosing between them is choosing where to intervene: Kisspeptin-10 for the neuroendocrine step that drives the cascade, the gonadotropin reagents for the receptor-level events it eventually produces. They are not alternatives and the readouts are not equivalent.
The KISS1 gene was first characterised as a metastasis suppressor, which is why the same peptide also appears in oncology-adjacent signalling work unrelated to reproductive endocrinology.
Handling
At ten residues the peptide is robust relative to the larger compounds in this catalogue, but the C-terminal amide and the tryptophan residue both make it worth protecting from light and from prolonged room-temperature holding.
It ships lyophilised and reconstitutes readily in bacteriostatic or sterile water at a volume chosen to reach the assay's target concentration. Low-binding labware is the usual choice for dilute working solutions. Lyophilised material is stored at -20°C protected from light; reconstituted solution is refrigerated at 2-8°C.
General laboratory handling of a chemical reagent only.
Certificates of Analysis
2 certificates are on file for Kisspeptin-10 — open any one to read the full report.
| Lot | Dose | Tested | Certificate |
|---|---|---|---|
| 100089-0935 | 10mg | 2026-08-20 | |
| 100032-0313 | 10mg | 2026-07-29 |
Key Areas of Research
- KISS1R / GPR54 receptor binding
- Neuroendocrine signaling cascades
- Metastasis-suppressor pathway research
- Structure-activity work across kisspeptin fragments
References
- Kotani M. et al. (2001). The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54. J Biol Chem, 276(37):34631–34636.
- de Roux N. et al. (2003). Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54. PNAS, 100(19):10972–10976.
Kisspeptin-10 — Frequently Asked Questions
- What is Kisspeptin-10?
- Kisspeptin-10 is the decapeptide Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂, corresponding to the bioactive C-terminal residues 45-54 of metastin. It is studied as a KISS1R (GPR54) agonist in laboratory models of neuroendocrine signaling.
- What is the CAS number for Kisspeptin-10?
- The CAS number for Kisspeptin-10 is 374675-21-5. Its molecular formula is C₆₃H₈₃N₁₇O₁₄ (MW 1,302.45 g/mol).
- What doses of Kisspeptin-10 are available wholesale?
- Wholesale Peptide Supply stocks Kisspeptin-10 in 10mg. Wholesale pricing is provided by quote based on order volume across 100–1,000 vials.
- Is Kisspeptin-10 third-party tested?
- Yes. Every lot of Kisspeptin-10 is tested by an independent third-party laboratory using HPLC/MS, and a per-lot Certificate of Analysis documenting identity and purity is included with every order at no charge, issued in the name of Wholesale Peptide Supply.
- Is Kisspeptin-10 for human use?
- No. Kisspeptin-10 is sold strictly as a chemical reagent for in-vitro laboratory research and is not for human or veterinary use. Wholesale Peptide Supply is not a pharmacy or compounding facility.
- How do I get wholesale pricing for Kisspeptin-10?
- Request a quote through our contact form or open a wholesale account. An account manager replies with volume pricing and lead times, typically within 10 minutes during business hours.
- Can I order Kisspeptin-10 in bulk?
- Yes. Kisspeptin-10 is available for bulk and wholesale orders, quoted by dose and volume, with the lower price earned per compound at 100 kits (1,000 vials). Submit the doses and quantities you need for a bulk quote.
Related Compounds
Melanocortin
Melanotan II
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PT-141
PT-141 (Bremelanotide) is a synthetic α-MSH analog selective for central MC3R/MC4R activity, studied for neuroendocrine signaling and vascular pathways.
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Oxytocin
Oxytocin is a cyclic nonapeptide synthesized in hypothalamic neurons. Through OXTR binding, it activates phospholipase C-mediated pathways. Studied for smooth muscle, CNS, and autonomic signaling.
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Melanotan I
Melanotan I (afamelanotide) is a 13-amino-acid analog of α-melanocyte stimulating hormone, [Nle⁴, D-Phe⁷]-α-MSH. It is studied as a melanocortin-1 receptor agonist in laboratory pigmentation and photoprotection models.
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PT-141 Liquid Spray
PT-141 (Bremelanotide) supplied as an atomized solution in a metered spray bottle. A synthetic α-MSH analog selective for central MC3R/MC4R activity, supplied in solution rather than as a lyophilised solid.
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MT-2 (Melanotan II) Liquid Spray
Melanotan II supplied as an atomized solution in a metered spray bottle — a cyclic α-MSH analog with broad melanocortin receptor activity.
View details →GLP-1 & Metabolic
Semaglutide
Semaglutide is a synthetic peptide analog that functions as a long-acting pathway agonist, structurally modified for extended half-life and improved target binding affinity. It is studied in preclinical and laboratory models for its ability to activate target pathways and modulate downstream molecular signaling associated with endocrine regulation.
View details →GLP-1 & Metabolic
Tirzepatide
Tirzepatide is a synthetic peptide that functions as a dual pathway agonist, designed as a once-weekly investigational compound studied in preclinical laboratory models for receptor-mediated signaling and modulation of downstream cascades.
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