Research Use Only. PT-141 is sold as a chemical reagent for in-vitro laboratory research, not for human or veterinary use. It is not a drug, supplement, or compounded preparation. It must be handled by qualified professionals. Wholesale Peptide Supply is not a pharmacy or compounding facility under 503A or 503B.
Wholesale PT-141 — Bulk Research Supply
Available sizes
In-stock orders ship same day when paid by 1 pm PT, Mon–Fri. Overnight available.
Buy PT-141 wholesale and in bulk from a US-based research peptide supplier. Every lot is sourced in the USA and third-party tested, with the lab and method on each lot's certificate. Bulk PT-141 is quoted by dose and volume from a 3-kit (30-vial) order minimum, mix and match across doses and compounds; lower prices are earned at 10 kits and again at 100 kits in the order, mix and match.
PT-141 (Bremelanotide) is a synthetic α-MSH analog selective for central MC3R/MC4R activity, studied for neuroendocrine signaling and vascular pathways.
Wholesale Catalog
Available Doses
Published per-vial wholesale pricing for PT-141. Sold in kits of 10 vials with a 3-kit (30-vial) order minimum, mix and match across doses and compounds; lower prices apply at 10 kits and at 1,000+ vials in the order. Contact us for larger or custom-volume quotes — answered the same day. Urgent? Text or call (714) 625-9215 — you’ll reach a real person in the United States, not a chatbot or an overseas call center.
PT-141 10mg
WPSPT10 · CAS 189691-06-3 · Melanocortin
- 1–9 kits
- $19.41/vial$17.47 paying by card
- 10–99 kits
- $15.53/vial$13.97 paying by card
- 100+ kits
- $12.42/vial$11.18 paying by card
10% off with card Every product, every volume band — taken off at checkout when you choose card.
Sold in kits of 10 vials · 3-kit order minimum, mix and match · price set by the total kits in your order (BAC water not counted)
Questions? Text a rep or call (714) 625-9215 — a real person in the US answers.
Overview
PT-141 (Bremelanotide) is a synthetic α-MSH analog selective for central MC3R/MC4R activity, studied for neuroendocrine signaling and vascular pathways.
History
Developed via structural modifications of Melanotan II to focus on central MC3R/MC4R receptor activity.
Structure and mechanism
PT-141, also catalogued as bremelanotide, is a cyclic heptapeptide and a metabolite of melanotan II — it is formed when the C-terminal amide of Melanotan II is replaced by a hydroxyl group. That single structural difference is what separates the two compounds, and it is the reason they are studied separately rather than treated as equivalents.
The cyclic lactam bridge constrains the peptide's conformation, which is what gives it selectivity across the melanocortin receptor subtypes in binding assays. In preclinical laboratory work it is studied principally as a melanocortin receptor agonist, with interest concentrated on MC3R and MC4R subtype selectivity relative to the MC1R-associated activity of Melanotan II.
Reconstitution and handling (research use)
PT-141 ships as a lyophilized powder in 10 mg vials, and is also stocked as a 15 mg nasal spray presentation. For in-vitro laboratory use it is reconstituted with bacteriostatic or sterile water at a volume chosen to reach the target assay concentration. The cyclic structure makes it more resistant to exopeptidase degradation than a comparable linear heptapeptide.
Lyophilized material is stored at -20°C protected from light; reconstituted solution is refrigerated at 2-8°C. General reagent handling guidance only — not for human or veterinary use.
Wholesale sourcing notes
PT-141 is the highest-volume compound in the melanocortin category, stocked in 10 mg vials and as a 15 mg nasal spray. Both presentations are sourced in the USA and independently verified by a third-party lab for identity, purity and quantitation.
Because PT-141 and Melanotan II differ by a single terminal modification, mass-spectrometry confirmation is the practical way to tell a correctly synthesized lot from a mislabeled one. A per-lot Certificate of Analysis is included with every order at no charge, issued in the name of Wholesale Peptide Supply.
Certificates of Analysis
2 certificates are on file for PT-141 — open any one to read the full report.
| Lot / Lab | Dose | Tested | Purity | Certificate |
|---|---|---|---|---|
| 100089-0943Optiq Health LabsRP-HPLC / LC-MS | 10mg | 2026-08-20 | — | |
| 100032-0297Optiq Health LabsRP-HPLC / LC-MS | 10mg | 2026-07-29 | — |
Key Areas of Research
- CNS MC3R/MC4R activity
- Melanocortin receptor modulation
- Autonomic and hemodynamic pathways
References
- Dorr R.T. et al. (1996). Life Sci 58(20):1777–1784.
- Diamond L.E. et al. (2004). J Sex Med 1(1):10–17.
PT-141 — Frequently Asked Questions
- What is PT-141?
- PT-141 (Bremelanotide) is a synthetic α-MSH analog selective for central MC3R/MC4R activity, studied for neuroendocrine signaling and vascular pathways.
- What is the CAS number for PT-141?
- The CAS number for PT-141 is 189691-06-3. Its molecular formula is C₅₀H₆₈N₁₄O₁₀ (MW 1,025.2 g/mol).
- What doses of PT-141 are available wholesale?
- Wholesale Peptide Supply stocks PT-141 in 10mg. Wholesale pricing is provided by quote based on order volume, from a 3-kit (30-vial) order minimum, mix and match across doses and compounds.
- Is PT-141 third-party tested?
- Yes. Every lot of PT-141 is tested by an independent third-party laboratory, and a per-lot Certificate of Analysis is included with every order at no charge, issued in the name of Wholesale Peptide Supply. The most recent published lot, 100089-0943 (10mg), was tested by Optiq Health Labs on 20 August 2026 by RP-HPLC / LC-MS. Every lot on file is listed with its certificate on this page.
- Is PT-141 for human use?
- No. PT-141 is sold strictly as a chemical reagent for in-vitro laboratory research and is not for human or veterinary use. Wholesale Peptide Supply is not a pharmacy or compounding facility.
- How do I get wholesale pricing for PT-141?
- Request a quote through our contact form or open a wholesale account. An account manager replies with volume pricing and lead times the same day. For anything urgent, text or call (714) 625-9215 to reach a real person in the US.
- Can I order PT-141 in bulk?
- Yes. PT-141 is available for bulk and wholesale orders, quoted by dose and volume, from a 3-kit (30-vial) order minimum, mix and match across doses and compounds, with lower prices at 10 kits and at 100 kits (1,000 vials) in the order. Submit the doses and quantities you need for a bulk quote.
- What is the difference between PT-141 and Melanotan II?
- PT-141 (bremelanotide) is a metabolite of Melanotan II, differing by the replacement of the C-terminal amide with a hydroxyl group. That single change alters receptor subtype selectivity in binding assays, which is why the two are studied separately rather than as equivalents. Wholesale Peptide Supply stocks both under separate SKUs.
- Is PT-141 available as a nasal spray?
- Yes. PT-141 is stocked both as a 10 mg lyophilized vial and as a 15 mg nasal spray bottle. Sprays are priced per single bottle with their own order minimum and volume break, which differ from the per-kit structure used for vials.
Related Compounds
Melanocortin
Melanotan II
Melanotan II is a synthetic cyclic heptapeptide analog of α-MSH acting as a nonselective melanocortin receptor agonist (MC1R, MC3R, MC4R, MC5R).
View details →Melanocortin
Oxytocin
Oxytocin is a cyclic nonapeptide synthesized in hypothalamic neurons. Through OXTR binding, it activates phospholipase C-mediated pathways. Studied for smooth muscle, CNS, and autonomic signaling.
View details →Melanocortin
Kisspeptin-10
Kisspeptin-10 is the decapeptide Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂, corresponding to the bioactive C-terminal residues 45-54 of metastin. It is studied as a KISS1R (GPR54) agonist in laboratory models of neuroendocrine signaling.
View details →Melanocortin
Melanotan I
Melanotan I (afamelanotide) is a 13-amino-acid analog of α-melanocyte stimulating hormone, [Nle⁴, D-Phe⁷]-α-MSH. It is studied as a melanocortin-1 receptor agonist in laboratory pigmentation and photoprotection models.
View details →Melanocortin
PT-141 Liquid Spray
PT-141 (Bremelanotide) supplied as an atomized solution in a metered spray bottle. A synthetic α-MSH analog selective for central MC3R/MC4R activity, supplied in solution rather than as a lyophilised solid.
View details →Melanocortin
MT-2 (Melanotan II) Liquid Spray
Melanotan II supplied as an atomized solution in a metered spray bottle — a cyclic α-MSH analog with broad melanocortin receptor activity.
View details →GLP-1 & Metabolic
Semaglutide
Semaglutide is a synthetic peptide analog that functions as a long-acting pathway agonist, structurally modified for extended half-life and improved target binding affinity. It is studied in preclinical and laboratory models for its ability to activate target pathways and modulate downstream molecular signaling associated with endocrine regulation.
View details →GLP-1 & Metabolic
Tirzepatide
Tirzepatide is a synthetic peptide that functions as a dual pathway agonist, designed as a once-weekly investigational compound studied in preclinical laboratory models for receptor-mediated signaling and modulation of downstream cascades.
View details →