Research Use Only. Sermorelin is sold as a chemical reagent for in-vitro laboratory research, not for human or veterinary use. It is not a drug, supplement, or compounded preparation. It must be handled by qualified professionals. Wholesale Peptide Supply is not a pharmacy or compounding facility under 503A or 503B.
Wholesale Sermorelin — Bulk Research Supply
Available sizes
In-stock orders ship same day when paid by 1 pm PT, Mon–Fri. Overnight available.
Buy Sermorelin wholesale and in bulk from a US-based research peptide supplier. Every lot is sourced in the USA and third-party tested, with the lab and method on each lot's certificate. Bulk Sermorelin is quoted by dose and volume from a 3-kit (30-vial) order minimum, mix and match across doses and compounds; lower prices are earned at 10 kits and again at 100 kits in the order, mix and match.
Sermorelin is GHRH (1-29), the unmodified N-terminal 29-residue fragment of growth hormone releasing hormone and the shortest sequence retaining full GHRH receptor activity.
Wholesale Catalog
Available Doses
Published per-vial wholesale pricing for Sermorelin. Sold in kits of 10 vials with a 3-kit (30-vial) order minimum, mix and match across doses and compounds; lower prices apply at 10 kits and at 1,000+ vials in the order. Contact us for larger or custom-volume quotes — answered the same day. Urgent? Text or call (714) 625-9215 — you’ll reach a real person in the United States, not a chatbot or an overseas call center.
Sermorelin 10mg
WPSSM10 · CAS 86168-78-7 · Secretagogue Peptides
- 1–9 kits
- $38.46/vial$34.61 paying by card
- 10–99 kits
- $30.76/vial$27.69 paying by card
- 100+ kits
- $24.61/vial$22.15 paying by card
10% off with card Every product, every volume band — taken off at checkout when you choose card.
Sold in kits of 10 vials · 3-kit order minimum, mix and match · price set by the total kits in your order (BAC water not counted)
Questions? Text a rep or call (714) 625-9215 — a real person in the US answers.
Overview
Sermorelin is GHRH (1-29), the unmodified N-terminal 29-residue fragment of growth hormone releasing hormone and the shortest sequence retaining full GHRH receptor activity.
History
Characterized as the minimal active fragment of the 44-residue native GHRH, sermorelin became the reference GHRH analog and the structural starting point for the substituted analogs that followed, including modified GRF (1-29) and CJC-1295.
Structure and mechanism
Sermorelin is GHRH (1-29) — the unmodified N-terminal 29 residues of the 44-residue native growth hormone releasing hormone, and the shortest sequence that retains full GHRH receptor activity. That makes it the reference molecule for the entire GHRH analog class: every substituted analog that followed, including modified GRF (1-29) and CJC-1295, is a variation on this backbone.
Its defining research characteristic is what it lacks. Because it carries no stabilizing substitutions, sermorelin is cleaved rapidly by enzymatic degradation, which is precisely why it is used in laboratory models to study native-like pulsatile GHRH signaling and to serve as the unmodified baseline against which stabilized analogs are compared. At 3,357.9 g/mol it is the smallest of the GHRH-class compounds stocked.
Reconstitution and handling (research use)
Wholesale sermorelin ships lyophilized. For in-vitro laboratory work it is reconstituted with bacteriostatic or sterile water and swirled gently until clear. The handling consideration specific to this compound is its degradation profile: unmodified GHRH fragments are markedly less stable in solution than their substituted counterparts, so reconstituted working stocks are typically prepared close to use rather than held, and the study's stability assumptions should reflect that.
Lyophilized powder is generally stored at -20°C protected from light; reconstituted solution is refrigerated at 2–8°C. These notes describe general laboratory handling of a chemical reagent only — not human or veterinary use.
Wholesale sourcing notes
Sermorelin is stocked wholesale in a 10 mg presentation. Every lot is US-sourced and independently verified by a third-party lab for identity, purity, and quantitation, with a per-lot COA included in every order.
Because it is the unmodified reference fragment, sermorelin is most often ordered alongside the stabilized analogs it is compared against — tesamorelin, CJC-1295, and ipamorelin. A comparative panel can be assembled in a single order from 1 kit of each compound (3 kits per order, mix and match), with lower prices at 10 and 100 kits in the order.
Also in this research area
If you stock Sermorelin, see also Tesamorelin and Tesamorelin / Ipamorelin Blend. Each page lists its sizes and per-vial pricing.
Certificates of Analysis
4 certificates are on file for Sermorelin — open any one to read the full report.
| Lot / Lab | Dose | Tested | Purity | Certificate |
|---|---|---|---|---|
| MT-20260720Optiq Health LabsRP-HPLC / LAL | 5mg | 2026-10-08 | 99.6%Endotoxin Pass (≤0.05 EU/mg) | |
| 100089-0955Optiq Health LabsRP-HPLC / LC-MS | 10mg | 2026-08-20 | — | |
| 100089-0954Optiq Health LabsRP-HPLC / LC-MS | 5mg | 2026-08-20 | — | |
| 100057-0615Optiq Health LabsRP-HPLC / LC-MS | 10mg | 2026-08-05 | — |
Key Areas of Research
- GHRH receptor binding and activation
- Pulsatile signaling research models
- Comparative studies vs. modified GRF (1-29) and CJC-1295
- Enzymatic degradation of unmodified GHRH fragments
References
- Guillemin R. et al. (1982). Growth hormone-releasing factor from a human pancreatic tumor. Science, 218(4572):585–587.
- Prakash A. & Goa K.L. (1999). Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency. BioDrugs, 12(2):139–157.
Sermorelin — Frequently Asked Questions
- What is Sermorelin?
- Sermorelin is GHRH (1-29), the unmodified N-terminal 29-residue fragment of growth hormone releasing hormone and the shortest sequence retaining full GHRH receptor activity.
- What is the CAS number for Sermorelin?
- The CAS number for Sermorelin is 86168-78-7. Its molecular formula is C₁₄₉H₂₄₆N₄₄O₄₂S (MW 3,357.9 g/mol).
- What doses of Sermorelin are available wholesale?
- Wholesale Peptide Supply stocks Sermorelin in 10mg. Wholesale pricing is provided by quote based on order volume, from a 3-kit (30-vial) order minimum, mix and match across doses and compounds.
- Is Sermorelin third-party tested?
- Yes. Every lot of Sermorelin is tested by an independent third-party laboratory, and a per-lot Certificate of Analysis documenting identity and purity is included with every order at no charge, issued in the name of Wholesale Peptide Supply. The most recent published lot, MT-20260720 (5mg), was tested by Optiq Health Labs on 8 October 2026 by RP-HPLC / LAL: purity 99.6%, endotoxin Pass (≤0.05 EU/mg). Every lot on file is listed with its certificate on this page.
- Is Sermorelin for human use?
- No. Sermorelin is sold strictly as a chemical reagent for in-vitro laboratory research and is not for human or veterinary use. Wholesale Peptide Supply is not a pharmacy or compounding facility.
- How do I get wholesale pricing for Sermorelin?
- Request a quote through our contact form or open a wholesale account. An account manager replies with volume pricing and lead times the same day. For anything urgent, text or call (714) 625-9215 to reach a real person in the US.
- Can I order Sermorelin in bulk?
- Yes. Sermorelin is available for bulk and wholesale orders, quoted by dose and volume, from a 3-kit (30-vial) order minimum, mix and match across doses and compounds, with lower prices at 10 kits and at 100 kits (1,000 vials) in the order. Submit the doses and quantities you need for a bulk quote.
- How does sermorelin relate to CJC-1295 and modified GRF (1-29)?
- Sermorelin is the unmodified GHRH (1-29) backbone that both are built from. Modified GRF (1-29) and CJC-1295 add substitutions that resist enzymatic cleavage and extend the window of receptor engagement. In laboratory models sermorelin therefore serves as the native-like baseline against which those stabilized analogs are compared; the compounds are not interchangeable.
- Why is sermorelin less stable than other GHRH analogs?
- It carries no stabilizing substitutions. Sermorelin is the plain N-terminal 29-residue fragment of native GHRH, so it is subject to the same rapid enzymatic degradation as the native hormone. That property is the reason it is used to model native-like pulsatile signaling, and it is why reconstituted working stocks are typically prepared close to the time of use.
Related Compounds
Secretagogue Peptides
Tesamorelin
Tesamorelin is a synthetic analog of growth hormone releasing hormone built on the full 44-residue GHRH sequence, carrying an N-terminal trans-3-hexenoyl modification that resists enzymatic cleavage and extends the window of GHRH receptor engagement relative to native GHRH.
View details →Secretagogue Peptides
Ipamorelin
Ipamorelin is a synthetic pentapeptide and selective secretagogue-type agonist with minimal off-target pathway interference, used to study endocrine signaling and somatotroph axis modulation.
View details →Secretagogue Peptides
CJC-1295 w/DAC
CJC-1295 with DAC is a modified GHRH analog with prolonged half-life through albumin binding, enabling sustained somatotroph axis activation in experimental models.
View details →Secretagogue Peptides
CJC/IPA No DAC Blend
Combines CJC-1295 No DAC with Ipamorelin to target two complementary signaling pathways. The No DAC variant maintains a shorter duration of action enabling pulsatile GH dynamics.
View details →Secretagogue Peptides
IGF-LR3
IGF-LR3 (Long Arg3 IGF-1) is a synthetic IGF-1 analog with reduced IGFBP binding and significantly extended half-life, used to investigate IGF-1 receptor-mediated signaling and metabolic regulation.
View details →Secretagogue Peptides
CJC-1295 (no DAC)
CJC-1295 without DAC — also called modified GRF (1-29) — is a GHRH analog carrying four amino acid substitutions that resist enzymatic cleavage, without the drug affinity complex that extends the DAC variant's half-life.
View details →Secretagogue Peptides
GHRP-2 Acetate
GHRP-2 (pralmorelin) is a synthetic hexapeptide growth hormone secretagogue with the sequence D-Ala-D-2Nal-Ala-Trp-D-Phe-Lys-NH₂, studied as a ghrelin receptor agonist in laboratory models.
View details →Secretagogue Peptides
GHRP-6 Acetate
GHRP-6 is a synthetic hexapeptide growth hormone secretagogue with the sequence His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂. It was the first of the GHRP series to be widely characterized and remains a common reference compound in secretagogue research.
View details →