What is the CAS number for Sermorelin?

The CAS number for Sermorelin is 86168-78-7. Its molecular formula is C₁₄₉H₂₄₆N₄₄O₄₂S (MW 3,357.9 g/mol).

What doses of Sermorelin are available wholesale?

Wholesale Peptide Supply stocks Sermorelin in 10mg. Wholesale pricing is provided by quote based on order volume across 100–1,000 vials.

Is Sermorelin third-party tested?

Yes. Every lot of Sermorelin is tested by an independent third-party laboratory using HPLC/MS, and a per-lot Certificate of Analysis documenting identity and purity is available as a paid add-on.

Is Sermorelin for human use?

No. Sermorelin is sold strictly as a chemical reagent for in-vitro laboratory research and is not for human or veterinary use. Wholesale Peptide Supply is not a pharmacy or compounding facility.

How do I get wholesale pricing for Sermorelin?

Request a quote through our contact form or open a wholesale account. An account manager replies with volume pricing and lead times, typically within 10 minutes during business hours.

Can I order Sermorelin in bulk?

Yes. Sermorelin is available for bulk and wholesale orders, quoted by dose and volume, with the lower price earned per compound at 100 kits (1,000 vials). Submit the doses and quantities you need for a bulk quote; all material is sourced in the USA and third-party HPLC/MS tested.

How does sermorelin relate to CJC-1295 and modified GRF (1-29)?

Sermorelin is the unmodified GHRH (1-29) backbone that both are built from. Modified GRF (1-29) and CJC-1295 add substitutions that resist enzymatic cleavage and extend the window of receptor engagement. In laboratory models sermorelin therefore serves as the native-like baseline against which those stabilized analogs are compared; the compounds are not interchangeable.

Why is sermorelin less stable than other GHRH analogs?

It carries no stabilizing substitutions. Sermorelin is the plain N-terminal 29-residue fragment of native GHRH, so it is subject to the same rapid enzymatic degradation as the native hormone. That property is the reason it is used to model native-like pulsatile signaling, and it is why reconstituted working stocks are typically prepared close to the time of use.

Research Use Only. Sermorelin is sold as a chemical reagent for in-vitro laboratory research. It is not a drug, supplement, or compounded preparation, and it is not for human or veterinary use. Wholesale Peptide Supply is not a pharmacy or compounding facility under 503A or 503B.

Growth HormoneCAS 86168-78-7

Wholesale Sermorelin — Bulk Research Supply

Buy Sermorelin wholesale and in bulk from a US-based research peptide supplier. Every lot is sourced in the USA and third-party third-party tested via HPLC/MS. Bulk Sermorelin is quoted by dose and volume from a 100-vial mix-and-match minimum; volume pricing is earned per compound at 100 kits.

Sermorelin is GHRH (1-29), the unmodified N-terminal 29-residue fragment of growth hormone releasing hormone and the shortest sequence retaining full GHRH receptor activity.

Wholesale Catalog

Available Doses

Published per-vial wholesale pricing for Sermorelin. Sold in kits of 10 vials with a 100-vial order minimum you can mix and match across compounds; volume pricing applies at 1,000+ vials. Contact us for larger or custom-volume quotes — typically answered within 10 minutes during business hours.

Sermorelin 10mg

WPSSM10 · CAS 86168-78-7 · Growth Hormone

$30.76/vial · under 100 kits · $24.61/vial · 100+ kits of this item

Sold in kits of 10 vials · 100-vial order minimum (mix & match across compounds) · 100+ kits of this item unlocks the lower price

Quantity

10 vials

1 kit

Request a custom quote

Overview

Sermorelin is GHRH (1-29), the unmodified N-terminal 29-residue fragment of growth hormone releasing hormone and the shortest sequence retaining full GHRH receptor activity.

History

Characterized as the minimal active fragment of the 44-residue native GHRH, sermorelin became the reference GHRH analog and the structural starting point for the substituted analogs that followed, including modified GRF (1-29) and CJC-1295.

Structure and mechanism

Sermorelin is GHRH (1-29) — the unmodified N-terminal 29 residues of the 44-residue native growth hormone releasing hormone, and the shortest sequence that retains full GHRH receptor activity. That makes it the reference molecule for the entire GHRH analog class: every substituted analog that followed, including modified GRF (1-29) and CJC-1295, is a variation on this backbone.

Its defining research characteristic is what it lacks. Because it carries no stabilizing substitutions, sermorelin is cleaved rapidly by enzymatic degradation, which is precisely why it is used in laboratory models to study native-like pulsatile GHRH signaling and to serve as the unmodified baseline against which stabilized analogs are compared. At 3,357.9 g/mol it is the smallest of the GHRH-class compounds stocked.

Reconstitution and handling (research use)

Wholesale sermorelin ships lyophilized. For in-vitro laboratory work it is reconstituted with bacteriostatic or sterile water and swirled gently until clear. The handling consideration specific to this compound is its degradation profile: unmodified GHRH fragments are markedly less stable in solution than their substituted counterparts, so reconstituted working stocks are typically prepared close to use rather than held, and the study's stability assumptions should reflect that.

Lyophilized powder is generally stored at -20°C protected from light; reconstituted solution is refrigerated at 2–8°C. These notes describe general laboratory handling of a chemical reagent only — not human or veterinary use.

Wholesale sourcing notes

Sermorelin is stocked wholesale in a 10 mg presentation. Every lot is US-sourced and independently verified by third-party HPLC/MS for identity, purity, and quantitation, with a per-lot COA available as a paid add-on.

Because it is the unmodified reference fragment, sermorelin is most often ordered alongside the stabilized analogs it is compared against — tesamorelin, CJC-1295, and ipamorelin. The 100-vial mix-and-match minimum lets a comparative panel be assembled in a single order, with volume pricing across the 100, 250, 500, and 1,000-vial bands.

Certificates of Analysis

Every lot of Sermorelin is tested by an independent third-party laboratory using HPLC/MS. 3 certificates are on file below — open any one to read the full report.

Lot	Dose	Tested
100089-0955	10mg	2026-08-20
100089-0954	5mg	2026-08-20
100057-0615	10mg	2026-08-05

Key Areas of Research

GHRH receptor binding and activation
Pulsatile signaling research models
Comparative studies vs. modified GRF (1-29) and CJC-1295
Enzymatic degradation of unmodified GHRH fragments

References

Guillemin R. et al. (1982). Growth hormone-releasing factor from a human pancreatic tumor. Science, 218(4572):585–587.
Prakash A. & Goa K.L. (1999). Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency. BioDrugs, 12(2):139–157.

Sermorelin — Frequently Asked Questions

What is Sermorelin?: Sermorelin is GHRH (1-29), the unmodified N-terminal 29-residue fragment of growth hormone releasing hormone and the shortest sequence retaining full GHRH receptor activity.
What is the CAS number for Sermorelin?: The CAS number for Sermorelin is 86168-78-7. Its molecular formula is C₁₄₉H₂₄₆N₄₄O₄₂S (MW 3,357.9 g/mol).
What doses of Sermorelin are available wholesale?: Wholesale Peptide Supply stocks Sermorelin in 10mg. Wholesale pricing is provided by quote based on order volume across 100–1,000 vials.
Is Sermorelin third-party tested?: Yes. Every lot of Sermorelin is tested by an independent third-party laboratory using HPLC/MS, and a per-lot Certificate of Analysis documenting identity and purity is available as a paid add-on.
Is Sermorelin for human use?: No. Sermorelin is sold strictly as a chemical reagent for in-vitro laboratory research and is not for human or veterinary use. Wholesale Peptide Supply is not a pharmacy or compounding facility.
How do I get wholesale pricing for Sermorelin?: Request a quote through our contact form or open a wholesale account. An account manager replies with volume pricing and lead times, typically within 10 minutes during business hours.
Can I order Sermorelin in bulk?: Yes. Sermorelin is available for bulk and wholesale orders, quoted by dose and volume, with the lower price earned per compound at 100 kits (1,000 vials). Submit the doses and quantities you need for a bulk quote; all material is sourced in the USA and third-party HPLC/MS tested.
How does sermorelin relate to CJC-1295 and modified GRF (1-29)?: Sermorelin is the unmodified GHRH (1-29) backbone that both are built from. Modified GRF (1-29) and CJC-1295 add substitutions that resist enzymatic cleavage and extend the window of receptor engagement. In laboratory models sermorelin therefore serves as the native-like baseline against which those stabilized analogs are compared; the compounds are not interchangeable.
Why is sermorelin less stable than other GHRH analogs?: It carries no stabilizing substitutions. Sermorelin is the plain N-terminal 29-residue fragment of native GHRH, so it is subject to the same rapid enzymatic degradation as the native hormone. That property is the reason it is used to model native-like pulsatile signaling, and it is why reconstituted working stocks are typically prepared close to the time of use.

Research Use Only

All products are intended solely for laboratory research purposes and are not for human or animal consumption. Must be handled by qualified professionals.